WISP2 抗体 (AA 87-116)
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- 抗原 See all WISP2 抗体
- WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))
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抗原表位
- AA 87-116
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WISP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This WISP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-116 amino acids from the Central region of human WISP2.
- 克隆位点
- RB2114
- 亚型
- Ig Fraction
- Top Product
- Discover our top product WISP2 Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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WISP-2 in human gastric cancer and its potential metastatic suppressor role in gastric cancer cells mediated by JNK and PLC-? pathways." in: British journal of cancer, Vol. 113, Issue 6, pp. 921-33, (2015) (PubMed).
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WISP-2 in human gastric cancer and its potential metastatic suppressor role in gastric cancer cells mediated by JNK and PLC-? pathways." in: British journal of cancer, Vol. 113, Issue 6, pp. 921-33, (2015) (PubMed).
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- 抗原
- WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))
- 别名
- WISP2 (WISP2 产品)
- 别名
- MGC84196 antibody, WISP2 antibody, ccn5 antibody, CCN5 antibody, CT58 antibody, CTGF-L antibody, Ccn5 antibody, Crgr4 antibody, Ctgfl antibody, Rcop1 antibody, WNT1 inducible signaling pathway protein 2 antibody, WNT1 inducible signaling pathway protein 2 S homeolog antibody, WISP2 antibody, wisp2.S antibody, wisp2 antibody, Wisp2 antibody
- 背景
- Wisp2 a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. Wisp2 lacks the CT domain which is implicated in dimerization and heparin binding. It is 72 % identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.
- 分子量
- 26825
- 基因ID
- 8839
- NCBI登录号
- NP_003872
- UniProt
- O76076
- 途径
- WNT signaling, Growth Factor Binding
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