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SIRT7 抗体 (C-Term)

SIRT7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1973 unconjugated
产品编号 ABIN390182
发货至: 中国
  • 抗原 See all SIRT7 抗体
    SIRT7 (Sirtuin 7 (SIRT7))
    抗原表位
    • 16
    • 10
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 331-360, C-Term
    适用
    • 53
    • 37
    • 28
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 68
    • 6
    • 2
    克隆类型
    • 72
    • 4
    多克隆
    标记
    • 35
    • 9
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIRT7 antibody is un-conjugated
    应用范围
    • 62
    • 31
    • 28
    • 16
    • 13
    • 13
    • 8
    • 8
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    B, M, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This SIRT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-360 amino acids from the C-terminal region of human SIRT7.
    克隆位点
    RB1973
    亚型
    Ig Fraction
    Top Product
    Discover our top product SIRT7 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:2000. IHC-P: 1:25
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Wang, Yi, Li, Cai, He, Ni, Zhou, Cheng, Jin, Fan, Qiu: "Down-regulation of sirtuin 3 is associated with poor prognosis in hepatocellular carcinoma after resection." in: BMC cancer, Vol. 14, pp. 297, (2014) (PubMed).

    Sestito, Madonna, Scarponi, Cianfarani, Failla, Cavani, Girolomoni, Albanesi: "STAT3-dependent effects of IL-22 in human keratinocytes are counterregulated by sirtuin 1 through a direct inhibition of STAT3 acetylation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 3, pp. 916-27, (2011) (PubMed).

    Alhazzazi, Kamarajan, Joo, Huang, Verdin, DSilva, Kapila: "Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer." in: Cancer, Vol. 117, Issue 8, pp. 1670-8, (2011) (PubMed).

  • 抗原
    SIRT7 (Sirtuin 7 (SIRT7))
    别名
    SIRT7 (SIRT7 产品)
    别名
    SIRT7 antibody, LOC796135 antibody, SIR2L7 antibody, sirtuin 7 antibody, phosphate cytidylyltransferase 2, ethanolamine antibody, SIRT7 antibody, sirt7 antibody, PCYT2 antibody, Sirt7 antibody
    背景
    SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
    分子量
    44898
    基因ID
    51547
    NCBI登录号
    NP_057622
    UniProt
    Q9NRC8
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