SIRT3 抗体 (C-Term)
(11 references)-
- 抗原 See all SIRT3 抗体
- SIRT3 (Sirtuin 3 (SIRT3))
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抗原表位
- AA 250-279, C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIRT3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This SIRT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-279 amino acids from the C-terminal region of human SIRT3.
- 克隆位点
- RB01967
- 亚型
- IgG
- Top Product
- Discover our top product SIRT3 Primary Antibody
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anti-Sirtuin 3 (SIRT3) (C-Term) antibody
SIRT3 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 3 (SIRT3) (AA 126-399) antibodySIRT3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 3 (SIRT3) (AA 127-303) antibodySIRT3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 3 (SIRT3) antibodyKO Validated SIRT3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Sirtuin 3 (SIRT3) (AA 155-290) antibodySIRT3 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 6B2A1 unconjugated
anti-Sirtuin 3 (SIRT3) (AA 304-334), (C-Term) antibodySIRT3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB25945 unconjugated
anti-Sirtuin 3 (SIRT3) (AA 250-279) antibodySIRT3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 3 (SIRT3) (AA 304-334) antibodySIRT3 适用: 人, 小鼠, Hamster WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 3 (SIRT3) (AA 5-257) antibodySIRT3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 3 (SIRT3) (AA 20-130) antibodySIRT3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:2000. WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze-thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
- 有效期
- 6 months
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: "Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons." in: Stem cell reports, Vol. 9, Issue 6, pp. 1839-1852, (2018) (PubMed).
: "Localization of sirtuins (SIRT1-7) in the aged mouse inner ear." in: Acta oto-laryngologica, pp. 1-12, (2015) (PubMed).
: "Activation of the aryl hydrocarbon receptor sensitizes mice to nonalcoholic steatohepatitis by deactivating mitochondrial sirtuin deacetylase Sirt3." in: Molecular and cellular biology, Vol. 33, Issue 10, pp. 2047-55, (2013) (PubMed).
: "Receptor-interacting protein (RIP) and Sirtuin-3 (SIRT3) are on opposite sides of anoikis and tumorigenesis." in: Cancer, Vol. 118, Issue 23, pp. 5800-10, (2012) (PubMed).
: "Integration of ?-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 36, pp. 12630-40, (2012) (PubMed).
: "PPAR?-LXR as a novel metabolostatic signalling axis in skeletal muscle that acts to optimize substrate selection in response to nutrient status." in: The Biochemical journal, Vol. 437, Issue 3, pp. 521-30, (2011) (PubMed).
: "FoxO1 mediates an autofeedback loop regulating SIRT1 expression." in: The Journal of biological chemistry, Vol. 286, Issue 7, pp. 5289-99, (2011) (PubMed).
: "Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer." in: Cancer, Vol. 117, Issue 8, pp. 1670-8, (2011) (PubMed).
: "Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway." in: The Journal of biological chemistry, Vol. 285, Issue 5, pp. 3133-44, (2010) (PubMed).
: "Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice." in: The Journal of clinical investigation, Vol. 119, Issue 9, pp. 2758-71, (2009) (PubMed).
: "SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70." in: Molecular and cellular biology, Vol. 28, Issue 20, pp. 6384-401, (2008) (PubMed).
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: "Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons." in: Stem cell reports, Vol. 9, Issue 6, pp. 1839-1852, (2018) (PubMed).
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- 抗原
- SIRT3 (Sirtuin 3 (SIRT3))
- 别名
- SIRT3 (SIRT3 产品)
- 别名
- zgc:158774 antibody, sirtuin antibody, SIR2L3 antibody, 2310003L23Rik antibody, AI848213 antibody, Sir2l3 antibody, sirtuin 3 antibody, sirt3 antibody, SIRT3 antibody, Sirt3 antibody
- 背景
- SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The SIRT3 is included in class I of the sirtuin family.
- 分子量
- 43573
- 基因ID
- 23410
- NCBI登录号
- NP_001017524, NP_036371
- UniProt
- Q9NTG7
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