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OASL 抗体 (C-Term)

OASL 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1948 unconjugated
产品编号 ABIN390168
发货至: 中国
  • 抗原 See all OASL 抗体
    OASL (2'-5'-Oligoadenylate Synthetase-Like (OASL))
    抗原表位
    • 15
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 484-514, C-Term
    适用
    • 22
    • 20
    • 19
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 37
    克隆类型
    • 37
    多克隆
    标记
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OASL antibody is un-conjugated
    应用范围
    • 15
    • 13
    • 13
    • 13
    • 9
    • 5
    • 5
    • 3
    • 3
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This OASL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-514 amino acids from the C-terminal region of human OASL.
    克隆位点
    RB1948
    亚型
    Ig Fraction
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Forero, Giacobbi, McCormick, Gjoerup, Bakkenist, Pipas, Sarkar: "Simian virus 40 large T antigen induces IFN-stimulated genes through ATR kinase." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 12, pp. 5933-42, (2014) (PubMed).

    Forero, Moore, Sarkar: "Role of IRF4 in IFN-stimulated gene induction and maintenance of Kaposi sarcoma-associated herpesvirus latency in primary effusion lymphoma cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 3, pp. 1476-85, (2013) (PubMed).

    Ishibashi, Wakita, Esumi: "2',5'-Oligoadenylate synthetase-like gene highly induced by hepatitis C virus infection in human liver is inhibitory to viral replication in vitro." in: Biochemical and biophysical research communications, Vol. 392, Issue 3, pp. 397-402, (2010) (PubMed).

  • 抗原
    OASL (2'-5'-Oligoadenylate Synthetase-Like (OASL))
    别名
    OASL (OASL 产品)
    别名
    Oasl1 antibody, oasl9 antibody, 7530414C13Rik antibody, OASLd antibody, TRIP-14 antibody, TRIP14 antibody, p59 OASL antibody, p59-OASL antibody, p59OASL antibody, 2'-5'-oligoadenylate synthetase-like antibody, 2'-5' oligoadenylate synthetase-like 1 antibody, 2'-5'-oligoadenylate synthetase like antibody, 2'-5'-oligoadenylate synthase-like protein antibody, Oasl antibody, Oasl1 antibody, OASL antibody, LOC100356242 antibody, LOC100483471 antibody
    背景
    2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to degradation of RNA and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a highly-conserved family of interferon-induced enzymes. The predicted 514-amino acid human p59OASL (2-5A synthetases-like) protein shares a highly conserved N-terminal domain with other OASs. The C-terminal portion of p59OASL contains 2 ubiquitin-like domains. p59OASL is expressed in most tissues, with the highest levels in hematopoietic tissues, colon, and stomach.
    分子量
    59226
    基因ID
    8638
    NCBI登录号
    NP_001248754, NP_003724, NP_937856
    UniProt
    Q15646
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