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NOTCH3 抗体 (C-Term)

NOTCH3 适用: 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB02199 unconjugated
产品编号 ABIN390159
发货至: 中国
  • 抗原 See all NOTCH3 抗体
    NOTCH3 (Notch 3 (NOTCH3))
    抗原表位
    • 13
    • 10
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 2291-2321, C-Term
    适用
    • 50
    • 16
    • 11
    • 1
    小鼠
    宿主
    • 33
    • 16
    • 3
    • 1
    • 1
    克隆类型
    • 37
    • 18
    多克隆
    标记
    • 29
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NOTCH3 antibody is un-conjugated
    应用范围
    • 27
    • 22
    • 20
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    H
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This NOTCH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2291-2321 amino acids from the C-terminal region of human NOTCH3.
    克隆位点
    RB02199
    亚型
    Ig Fraction
    Top Product
    Discover our top product NOTCH3 Primary Antibody
  • 应用备注
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Liu, Yang, Wang, Miao, Liu, Li, Zou, Li, Liang, Zeng, Chen: "The Expression of Notch 1 and Notch 3 in Gallbladder Cancer and Their Clinicopathological Significance." in: Pathology oncology research : POR, Vol. 22, Issue 3, pp. 483-92, (2017) (PubMed).

  • 抗原
    NOTCH3 (Notch 3 (NOTCH3))
    别名
    NOTCH3 (NOTCH3 产品)
    别名
    CADASIL antibody, CASIL antibody, IMF2 antibody, AW229011 antibody, N3 antibody, hpbk antibody, fa14b08 antibody, notch5 antibody, wu:fa14b08 antibody, notch 3 antibody, NOTCH3 antibody, Notch3 antibody, notch3 antibody
    背景
    NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
    分子量
    243631
    基因ID
    4854
    NCBI登录号
    NP_000426
    UniProt
    Q9UM47
    途径
    Notch Signaling
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