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MLLT1 抗体 (C-Term)

MLLT1 适用: 人 WB 宿主: 兔 Polyclonal RB1927-1928 unconjugated
产品编号 ABIN390126
发货至: 中国
  • 抗原 See all MLLT1 抗体
    MLLT1 (MLLT1, super elongation complex subunit (MLLT1))
    抗原表位
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 523-552, C-Term
    适用
    • 24
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 21
    • 3
    克隆类型
    • 22
    • 2
    多克隆
    标记
    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    This MLLT1 antibody is un-conjugated
    应用范围
    • 17
    • 12
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This MLLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 523-552 amino acids from the C-terminal region of human MLLT1.
    克隆位点
    RB1927-1928
    亚型
    Ig Fraction
    Top Product
    Discover our top product MLLT1 Primary Antibody
  • 应用备注
    WB: 1:2000. WB: 1:2000. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Bitoun, Oliver, Davies: "The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling." in: Human molecular genetics, Vol. 16, Issue 1, pp. 92-106, (2007) (PubMed).

  • 抗原
    MLLT1 (MLLT1, super elongation complex subunit (MLLT1))
    别名
    MLLT1 (MLLT1 产品)
    背景
    Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11,19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.
    分子量
    62056
    基因ID
    4298
    NCBI登录号
    NP_005925
    UniProt
    Q03111
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