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EDG4 抗体 (N-Term)

Name: EDG4 抗体 (N-Term)
SKU: ABIN390085
Availability: OutOfStock

LPAR2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1827 unconjugated

Western blot analysis of lysate from MDA-MB-231 cell line, using EDG4 Antibody (N18) (ABIN390085 and ABIN2840604). (EDG4 抗体 (N-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (EDG4 抗体 (N-Term))

IHC (p)

The anti-EDG4 N-term Antibody (ABIN390085 and ABIN2840604) is used in Western blot to detect EDG4 in HL60 lysate. (EDG4 抗体 (N-Term))

3 images

(5 references)

产品编号 ABIN390085

发货至: 中国

Datasheet as PDF

抗原 See all EDG4 (LPAR2) 抗体

EDG4 (LPAR2) (Lysophosphatidic Acid Receptor 2 (LPAR2))
抗原表位
16

7

4

4

3

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 3-32, N-Term
适用
41

27

21

2
人
宿主
56

1
兔
Compatible Secondaries
克隆类型
57
多克隆
标记
25

4

4

4

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This EDG4 antibody is un-conjugated
应用范围
24

22

15

13

13

11

9

7

4

3

2

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

Pr

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This EDG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-32 amino acids from the N-terminal region of human EDG4.

克隆位点

RB1827

亚型

Ig Fraction

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LPAR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

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anti-Lysophosphatidic Acid Receptor 2 (LPAR2) (AA 250-350) antibody
LPAR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Lysophosphatidic Acid Receptor 2 (LPAR2) (AA 271-320) antibody
LPAR2 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Lysophosphatidic Acid Receptor 2 (LPAR2) (AA 290-339) antibody
LPAR2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Yamauchi, Yamamura, Katase, Itadani, Okada, Kobiki, Nakamura, Yamaguchi, Kuribayashi: "Evaluation of pancreatic cancer cell migration with multiple parameters in vitro by using an optical real-time cell mobility assay device." in: BMC cancer, Vol. 17, Issue 1, pp. 234, (2017) (PubMed).

Geng, Lan, Singha, Gilchrist, Weinreb, Violette, Weinberg, Saikumar, Venkatachalam: "Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and G?q-mediated Rho and ?v?6 integrin-dependent activation of TGF-?." in: The American journal of pathology, Vol. 181, Issue 4, pp. 1236-49, (2012) (PubMed).

Bernhart, Kollroser, Rechberger, Reicher, Heinemann, Schratl, Hallström, Wintersperger, Nusshold, DeVaney, Zorn-Pauly, Malli, Graier, Malle, Sattler: "Lysophosphatidic acid receptor activation affects the C13NJ microglia cell line proteome leading to alterations in glycolysis, motility, and cytoskeletal architecture." in: Proteomics, Vol. 10, Issue 1, pp. 141-58, (2010) (PubMed).

Todorova, Fuentes, Soria, Nadal, Quesada: "Lysophosphatidic acid induces Ca2+ mobilization and c-Myc expression in mouse embryonic stem cells via the phospholipase C pathway." in: Cellular signalling, Vol. 21, Issue 4, pp. 523-8, (2009) (PubMed).

Horak, Lee, Elkahloun, Boissan, Dumont, Maga, Arnaud-Dabernat, Palmieri, Stetler-Stevenson, Lacombe, Meltzer, Steeg: "Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2." in: Cancer research, Vol. 67, Issue 15, pp. 7238-46, (2007) (PubMed).
抗原

EDG4 (LPAR2) (Lysophosphatidic Acid Receptor 2 (LPAR2))

别名

EDG4 (LPAR2 产品)

别名

EDG-4 antibody, EDG4 antibody, LPA-2 antibody, LPA2 antibody, lpa2 antibody, Gpbar1 antibody, Edg4 antibody, IPA2 antibody, Pbx4 antibody, RGD1561336 antibody, zgc:101053 antibody, lysophosphatidic acid receptor 2 antibody, lysophosphatidic acid receptor 2 S homeolog antibody, G protein-coupled bile acid receptor 1 antibody, growth hormone releasing hormone receptor antibody, lysophosphatidic acid receptor 2a antibody, LPAR2 antibody, lpar2.S antibody, GPBAR1 antibody, Lpar2 antibody, GHRHR antibody, lpar2a antibody

背景

EDG4 is a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins.

分子量

39084

基因ID

9170

NCBI登录号

NP_004711

UniProt

Q9HBW0