-
- 抗原 See all EPR1 抗体
- EPR1 (Early-Phytochrome-Responsive1 (EPR1))
- 抗原表位
- AA 308-337, C-Term
- 适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This EPR1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This EPR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-337 amino acids from the C-terminal region of human EPR1.
- 克隆位点
- RB1796
- 亚型
- Ig Fraction
- Top Product
- Discover our top product EPR1 Primary Antibody
-
anti-Early-Phytochrome-Responsive1 (EPR1) (AA 308-337) antibody
EPR1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
-
- 抗原
- EPR1 (Early-Phytochrome-Responsive1 (EPR1))
- 别名
- EPR1 (EPR1 产品)
- 背景
- Cellular receptors for blood proteases regulate chemotaxis, extracellular proteolysis, and growth behavior of normal and malignant cells. Effector cell protease receptor-1 (EPR1) is a receptor for the coagulation protease factor Xa. EPR1 is characterized by a cysteine-rich extracellular module, a single membrane-spanning domain, and a serine-rich cytoplasmic tail featuring at least 15 potential phosphorylation sites. EPR1 also contains 2 N-linked glycosylation sites, 4 O-linked glycosylation sites, and a chondroitin sulfate attachment site, which may provide anchoring for carbohydrate chains, EPR1 transfectants bind to factor Xa in a specific and saturable manner, and in the absence of factor V/Va promote prothrombin activation in a factor Xa concentration-dependent reaction. Activated platelets and megakaryocytes express EPR1. Both EPR1 and membrane-bound factor Va are thought to be required to mediate factor Xa binding to the activated platelet to form a functional prothrombinase complex.
- 分子量
- 36826
- UniProt
- Q14868
- 途径
- Apoptosis, Cell Division Cycle
-
You are here:
