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EPR1 抗体 (C-Term)

EPR1 适用: 人 WB 宿主: 兔 Polyclonal RB1796 unconjugated
产品编号 ABIN390071
发货至: 中国
  • 抗原 See all EPR1 抗体
    EPR1 (Early-Phytochrome-Responsive1 (EPR1))
    抗原表位
    AA 308-337, C-Term
    适用
    宿主
    • 18
    克隆类型
    • 18
    多克隆
    标记
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EPR1 antibody is un-conjugated
    应用范围
    • 18
    • 13
    • 3
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This EPR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-337 amino acids from the C-terminal region of human EPR1.
    克隆位点
    RB1796
    亚型
    Ig Fraction
    Top Product
    Discover our top product EPR1 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    EPR1 (Early-Phytochrome-Responsive1 (EPR1))
    别名
    EPR1 (EPR1 产品)
    背景
    Cellular receptors for blood proteases regulate chemotaxis, extracellular proteolysis, and growth behavior of normal and malignant cells. Effector cell protease receptor-1 (EPR1) is a receptor for the coagulation protease factor Xa. EPR1 is characterized by a cysteine-rich extracellular module, a single membrane-spanning domain, and a serine-rich cytoplasmic tail featuring at least 15 potential phosphorylation sites. EPR1 also contains 2 N-linked glycosylation sites, 4 O-linked glycosylation sites, and a chondroitin sulfate attachment site, which may provide anchoring for carbohydrate chains, EPR1 transfectants bind to factor Xa in a specific and saturable manner, and in the absence of factor V/Va promote prothrombin activation in a factor Xa concentration-dependent reaction. Activated platelets and megakaryocytes express EPR1. Both EPR1 and membrane-bound factor Va are thought to be required to mediate factor Xa binding to the activated platelet to form a functional prothrombinase complex.
    分子量
    36826
    UniProt
    Q14868
    途径
    Apoptosis, Cell Division Cycle
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