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MEK1 抗体 (pSer222)
MAP2K1
适用: 人
WB, DB
宿主: 兔
Polyclonal
RB15989
unconjugated
MEK1抗体详情
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抗原
See all MEK1 (MAP2K1) 抗体
MEK1 (MAP2K1)
(Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
抗原表位
All epitopes for MEK1 抗体
pSer222
适用
All reactivities for MEK1 抗体
人
宿主
All hosts for MEK1 抗体
兔
克隆类型
All clonalities for MEK1 抗体
多克隆
标记
All conjugates for MEK1 抗体
This MEK1 antibody is un-conjugated
应用范围
All applications for MEK1 抗体
Western Blotting (WB), Dot Blot (DB)
预测反应
D, Ha, M, Rb, Rat, X, C
纯化方法
This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This MEK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S222 of human MEK1.
克隆位点
RB15989
亚型
Ig Fraction
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Alternatives
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使用细节
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应用备注
WB: 1:500. DB: 1:500
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期
6 months
MEK1目标详情
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抗原
MEK1 (MAP2K1)
(Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
别名
MEK1 (MAP2K1 产品 )
别名
Mek1 antibody, CFC3 antibody, MAPKK1 antibody, MEK1 antibody, MKK1 antibody, PRKMK1 antibody, MEKK1 antibody, Prkmk1 antibody, mek-2 antibody, si:ch211-242m18.2 antibody, wu:fj56a12 antibody, wu:fj61b01 antibody, zgc:56557 antibody, ATMEK1 antibody, F20B18.180 antibody, F20B18_180 antibody, MAP kinase/ ERK kinase 1 antibody, MITOGEN ACTIVATED PROTEIN KINASE KINASE antibody, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 antibody, NMAPKK antibody, MEK antibody, mitogen activated protein kinase kinase 1 antibody, mitogen-activated protein kinase kinase 1 antibody, mitogen-activated protein kinase kinase 1 L homeolog antibody, MAP kinase/ ERK kinase 1 antibody, Map2k1 antibody, MAP2K1 antibody, map2k1.L antibody, map2k1 antibody, MEK1 antibody
背景
MEK1is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.
分子量
43439
基因ID
5604
NCBI登录号
NP_002746
UniProt
Q02750
途径
MAPK Pathway , RTK signaling , Interferon-gamma Pathway , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Toll-Like Receptors Cascades , Autophagy , Signaling of Hepatocyte Growth Factor Receptor , BCR Signaling
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