我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

Insulin Receptor 抗体 (pTyr1185)

Name: Insulin Receptor 抗体 (pTyr1185)
SKU: ABIN389937
Availability: OutOfStock

INSR 适用: 人 DB 宿主: 兔 Polyclonal RB15377 unconjugated

Dot blot analysis of anti-Phospho-INSR-p Antibody (ABIN389937 and ABIN2839751) on nitrocellulose membrane. (Insulin Receptor 抗体 (pTyr1185))

1 image

产品编号 ABIN389937

发货至: 中国

Datasheet as PDF

抗原 See all Insulin Receptor (INSR) 抗体

Insulin Receptor (INSR)
抗原表位
16

14

13

11

8

8

7

5

5

5

4

4

4

4

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr1185
适用
168

87

76

17

12

9

8

7

6

6

4

3

2

2

1

1

1

1

1

1

1

1
人
宿主
157

25

2

1
兔
Compatible Secondaries
克隆类型
146

39
多克隆
标记
118

15

14

5

4

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
This Insulin Receptor antibody is un-conjugated
应用范围
134

77

53

32

18

15

15

15

13

13

8

5

4

4

3

2

2

2

1

1

1

1
Dot Blot (DB)

预测反应

B, M, Rat, X, D

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This INSR Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1185 of human INSR.

克隆位点

RB15377

亚型

Ig Fraction

Top Product

Discover our top product INSR Primary Antibody
anti-Insulin Receptor (INSR) antibody
INSR 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C19 unconjugated

anti-Insulin Receptor (INSR) (AA 1024-1298) antibody
INSR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin Receptor (INSR) (AA 1027-1364) antibody
INSR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin Receptor (INSR) (AA 1101-1372) antibody
INSR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin Receptor (INSR) (C-Term) antibody
INSR 适用: 人, 小鼠, 大鼠, 犬, 猴, 马, Cow, 豚鼠, 兔, Pig, 小鸡, 绵羊, Hamster, Avian, Cat, 驴, 山羊 WB 宿主: 山羊 Polyclonal unconjugated

anti-Insulin Receptor (INSR) (C-Term) antibody
KO Validated INSR 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Insulin Receptor (INSR) (AA 51-150) antibody
INSR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Insulin Receptor (INSR) (AA 1325-1358) antibody
INSR 适用: 小鼠 WB 宿主: 兔 Polyclonal RB50340 unconjugated

anti-Insulin Receptor (INSR) (AA 1023-1298) antibody
INSR 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Insulin Receptor (INSR) (AA 27-57), (N-Term) antibody
INSR 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1421 unconjugated

应用备注

DB: 1:500

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
抗原

Insulin Receptor (INSR)

别名

INSR (INSR 产品)

背景

Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake, thereby mediating the metabolic functions of insulin. Binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). This protein can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1. After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked.

分子量

156333

基因ID

3643

NCBI登录号

NP_000199, NP_001073285

UniProt

P06213

途径

NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity