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ATM 抗体 (pSer1981)

Name: ATM 抗体 (pSer1981)
SKU: ABIN389888
Availability: OutOfStock

ATM 适用: 人 IF, DB 宿主: 兔 Polyclonal RB8121 unconjugated

Confocal immunofluorescent analysis ofPhospho-ATM-p Antibody (ABIN389888 and ABIN2839734) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (ATM 抗体 (pSer1981))

Dot blot analysis of anti-Phospho-ATM-p Antibody (ABIN389888 and ABIN2839734) on nitrocellulose membrane. (ATM 抗体 (pSer1981))

2 images

(1 reference)

产品编号 ABIN389888

发货至: 中国

Datasheet as PDF

抗原 See all ATM 抗体

ATM (Ataxia Telangiectasia Mutated (ATM))
抗原表位
28

16

15

13

9

8

7

7

7

6

5

4

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer1981
适用
150

75

32

1

1

1
人
宿主
129

22

5

2
兔
Compatible Secondaries
克隆类型
127

31
多克隆
标记
75

9

7

5

4

4

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

2

2
This ATM antibody is un-conjugated
应用范围
66

49

39

34

28

23

23

17

17

11

7

7

4

2

2

2

1
Immunofluorescence (IF), Dot Blot (DB)

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This Phospho-ATM-pS1981 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1981 of human ATM.

克隆位点

RB8121

亚型

Ig Fraction

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ATM 适用: 人 WB, IHC, ELISA, FACS, FM 宿主: 小鼠 Monoclonal 10H11-E12 unconjugated

anti-Ataxia Telangiectasia Mutated (ATM) (AA 1974-1988), (pSer1981) antibody
ATM 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FM 宿主: 小鼠 Monoclonal 10H11-E12 unconjugated

anti-Ataxia Telangiectasia Mutated (ATM) (C-Term) antibody
ATM 适用: 人, 小鼠 WB, IHC, ELISA, IP, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated

anti-Ataxia Telangiectasia Mutated (ATM) (AA 2681-2750) antibody
ATM 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (p), IF (cc), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Ataxia Telangiectasia Mutated (ATM) (AA 2484-2748) antibody
ATM 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Ataxia Telangiectasia Mutated (ATM) antibody
ATM 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Monoclonal 4E11 unconjugated Recombinant Antibody

anti-Ataxia Telangiectasia Mutated (ATM) (AA 1974-1988), (pSer1981) antibody (HRP)
ATM 适用: 人 WB, IHC, ELISA, FM 宿主: 小鼠 Monoclonal 10H11-E12 HRP

anti-Ataxia Telangiectasia Mutated (ATM) (AA 486-742) antibody
ATM 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Ataxia Telangiectasia Mutated (ATM) antibody
ATM 适用: 人 IHC, ELISA, FACS 宿主: 兔 Monoclonal 3G11 unconjugated Recombinant Antibody

anti-Ataxia Telangiectasia Mutated (ATM) antibody
ATM 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5C5 unconjugated

应用备注

IF: 1:10~50. DB: 1:500

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Matsuda, Sanpei, Wakai, Kubota, Osawa, Hirose, Sakata, Kobayashi, Fujimaki, Takamura, Yamagiwa, Yano, Ohkoshi, Aoyagi: "Hepatitis B virus X stimulates redox signaling through activation of ataxia telangiectasia mutated kinase." in: International journal of clinical and experimental pathology, Vol. 7, Issue 5, pp. 2032-43, (2015) (PubMed).
抗原

ATM (Ataxia Telangiectasia Mutated (ATM))

别名

ATM (ATM 产品)

别名

ATM antibody, Atm antibody, CG6535 antibody, Dmel\\CG6535 antibody, Tefu antibody, atm antibody, atm/tefu antibody, dATM antibody, tef antibody, Xatm antibody, at1 antibody, atdc antibody, tel1 antibody, telo1 antibody, AT1 antibody, ATA antibody, ATC antibody, ATD antibody, ATDC antibody, ATE antibody, TEL1 antibody, TELO1 antibody, AI256621 antibody, C030026E19Rik antibody, telomere fusion antibody, ATM serine/threonine kinase L homeolog antibody, ATM serine/threonine kinase antibody, ataxia telangiectasia mutated antibody, ataxia telangiectasia mutated (atm) antibody, serine/threonine-protein kinase ATM antibody, tefu antibody, atm.L antibody, atm antibody, ATM antibody, EDI_100660 antibody, CpipJ_CPIJ001772 antibody, BDBG_08252 antibody, PAAG_02532 antibody, MCYG_05088 antibody, VDBG_06833 antibody, ACLA_015700 antibody, LOC5565620 antibody, MGYG_07634 antibody, PGTG_14279 antibody, Atm antibody

背景

ATM belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates, thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2,checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. ATM and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in the gene encoding ATM are associated with ataxia telangiectasia, an autosomal recessive disorder.

分子量

350687

基因ID

472

NCBI登录号

NP_000042

UniProt

Q13315

途径

p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus