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- 抗原 See all AKT3 抗体
- AKT3 (V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))
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抗原表位
- pSer472
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AKT3 antibody is un-conjugated
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应用范围
- Dot Blot (DB)
- 预测反应
- M, Rat
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This AKT3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S472 of human AKT3.
- 克隆位点
- RB13331
- 亚型
- Ig Fraction
- Top Product
- Discover our top product AKT3 Primary Antibody
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- 应用备注
- DB: 1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-?B and PI3K/Akt3 signaling pathways." in: Scientific reports, Vol. 5, pp. 11614, (2015) (PubMed).
: "8-Methoxypsoralen Induces Intrinsic Apoptosis in HepG2 Cells: Involvement of Reactive Oxygen Species Generation and ERK1/2 Pathway Inhibition." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 37, Issue 1, pp. 361-74, (2015) (PubMed).
: "Axl mediates tumor invasion and chemosensitivity through PI3K/Akt signaling pathway and is transcriptionally regulated by slug in breast carcinoma." in: IUBMB life, Vol. 66, Issue 7, pp. 507-18, (2014) (PubMed).
: "Blockade of CCN6 (WISP3) activates growth factor-independent survival and resistance to anoikis in human mammary epithelial cells." in: Cancer research, Vol. 70, Issue 8, pp. 3340-50, (2010) (PubMed).
: "Akt1 mediates purinergic-dependent NOS3 activation in thick ascending limbs." in: American journal of physiology. Renal physiology, Vol. 297, Issue 3, pp. F646-52, (2009) (PubMed).
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Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-?B and PI3K/Akt3 signaling pathways." in: Scientific reports, Vol. 5, pp. 11614, (2015) (PubMed).
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- 抗原
- AKT3 (V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))
- 别名
- AKT3 (AKT3 产品)
- 别名
- MPPH antibody, PKB-GAMMA antibody, PKBG antibody, PRKBG antibody, RAC-PK-gamma antibody, RAC-gamma antibody, STK-2 antibody, AI851531 antibody, D930002M15Rik antibody, Nmf350 antibody, Pkbg antibody, AKT serine/threonine kinase 3 antibody, thymoma viral proto-oncogene 3 antibody, v-akt murine thymoma viral oncogene homolog 3b antibody, AKT3 antibody, Akt3 antibody, akt3b antibody
- 背景
- AKT3 is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1).
- 分子量
- 55775
- 基因ID
- 10000
- NCBI登录号
- NP_001193658, NP_005456, NP_859029
- UniProt
- Q9Y243
- 途径
- PI3K-Akt Signaling, RTK signaling, TLR signaling, Hepatitis C, VEGF Signaling
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