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c-MYC 抗体 (pThr58)

MYC 适用: 人 WB, DB 宿主: 兔 Polyclonal RB11187 unconjugated
产品编号 ABIN389723
发货至: 中国
  • 抗原 See all c-MYC (MYC) 抗体
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    抗原表位
    • 58
    • 48
    • 47
    • 40
    • 24
    • 22
    • 17
    • 15
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    pThr58
    适用
    • 360
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    • 1
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    宿主
    • 279
    • 98
    • 7
    • 5
    • 3
    • 1
    克隆类型
    • 273
    • 119
    多克隆
    标记
    • 191
    • 31
    • 24
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    • 8
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    This c-MYC antibody is un-conjugated
    应用范围
    • 287
    • 139
    • 97
    • 80
    • 77
    • 58
    • 56
    • 28
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    • 21
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    Western Blotting (WB), Dot Blot (DB)
    预测反应
    X, Zf, M, Rat, B, Pig, Sh
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This MYC Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T58 of human MYC.
    克隆位点
    RB11187
    亚型
    Ig Fraction
    Top Product
    Discover our top product MYC Primary Antibody
  • 应用备注
    WB: 1:1000. DB: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Yeh, Lu, Ou, Cheng: "I?B kinases increase Myc protein stability and enhance progression of breast cancer cells." in: Molecular cancer, Vol. 10, pp. 53, (2011) (PubMed).

  • 抗原
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    别名
    Myc Proto-Oncogene protein (MYC 产品)
    背景
    MYC participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.
    分子量
    48804
    基因ID
    4609
    NCBI登录号
    NP_002458
    UniProt
    P01106
    途径
    p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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