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c-MYC 抗体 (pThr58)

MYC 适用: 人 WB, DB 宿主: 兔 Polyclonal RB11187 unconjugated
产品编号 ABIN389723
发货至: 中国
  • 抗原 See all c-MYC (MYC) 抗体
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    抗原表位
    • 58
    • 47
    • 45
    • 40
    • 24
    • 22
    • 17
    • 15
    • 15
    • 14
    • 10
    • 8
    • 8
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr58
    适用
    • 375
    • 180
    • 133
    • 16
    • 15
    • 13
    • 13
    • 13
    • 10
    • 10
    • 8
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    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 294
    • 98
    • 7
    • 5
    • 3
    • 1
    克隆类型
    • 291
    • 116
    多克隆
    标记
    • 196
    • 32
    • 26
    • 24
    • 8
    • 8
    • 6
    • 6
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This c-MYC antibody is un-conjugated
    应用范围
    • 295
    • 147
    • 102
    • 80
    • 78
    • 61
    • 55
    • 28
    • 26
    • 20
    • 16
    • 13
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    • 1
    • 1
    • 1
    Western Blotting (WB), Dot Blot (DB)
    预测反应
    X, Zf, M, Rat, B, Pig, Sh
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This MYC Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T58 of human MYC.
    克隆位点
    RB11187
    亚型
    Ig Fraction
    Top Product
    Discover our top product MYC Primary Antibody
  • 应用备注
    WB: 1:1000. DB: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Yeh, Lu, Ou, Cheng: "I?B kinases increase Myc protein stability and enhance progression of breast cancer cells." in: Molecular cancer, Vol. 10, pp. 53, (2011) (PubMed).

  • 抗原
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    别名
    Myc Proto-Oncogene protein (MYC 产品)
    别名
    MRTL antibody, MYCC antibody, bHLHe39 antibody, c-Myc antibody, CMYC antibody, c-myc antibody, C-MYC antibody, LOC100136746 antibody, ARC antibody, B430311C09Rik antibody, MYC antibody, NOP antibody, Nop30 antibody, RNCMYC antibody, mMyc antibody, AU016757 antibody, Myc2 antibody, Niard antibody, Nird antibody, cmyc antibody, zc-myc antibody, c-myc II antibody, myc-B antibody, myc2 antibody, myc1 antibody, CMyc antibody, zgc:55680 antibody, CG10798 antibody, D-Myc antibody, DM antibody, DMYc antibody, Dm antibody, Dmel\CG10798 antibody, Dmyc antibody, EG:BACN5I9.1 antibody, anon-WO03040301.171 antibody, bHLHe57 antibody, c-MYC antibody, d-myc antibody, dMYC antibody, dMyc antibody, dMyc1 antibody, da antibody, dm antibody, dm/dMyc antibody, dm/myc antibody, dmyc antibody, dmyc1 antibody, l(1)G0139 antibody, l(1)G0354 antibody, l(1)G0359 antibody, myc antibody, MYC proto-oncogene, bHLH transcription factor antibody, v-myc myelocytomatosis viral oncogene homolog antibody, nucleolar protein 3 (apoptosis repressor with CARD domain) antibody, myelocytomatosis oncogene antibody, MYC proto-oncogene, bHLH transcription factor a antibody, MYC proto-oncogene, bHLH transcription factor L homeolog antibody, MYC proto-oncogene, bHLH transcription factor S homeolog antibody, v-myc myelocytomatosis viral oncogene homolog (avian) antibody, MYC proto-oncogene, bHLH transcription factor b antibody, CG10798 gene product from transcript CG10798-RB antibody, MYC antibody, LOC100136746 antibody, Nol3 antibody, Myc antibody, myca antibody, myc.L antibody, myc.S antibody, mycb antibody
    背景
    MYC participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.
    分子量
    48804
    基因ID
    4609
    NCBI登录号
    NP_002458
    UniProt
    P01106
    途径
    p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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