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STAT5A 抗体 (pTyr694)

Name: STAT5A 抗体 (pTyr694)
SKU: ABIN389668
Availability: OutOfStock

STAT5A 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB5956 unconjugated

Western blot analysis of anti-Phospho-STAT5 Pab (ABIN389668 and ABIN2839647) in HepG2 cell line lysate (35 μg/lane). (STAT5A 抗体 (pTyr694))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (STAT5A 抗体 (pTyr694))

IHC (p)

Fluorescent confocal image of an SY5Y cell stained with (ABIN389668 and ABIN2839647) Phospho-STAT5a antibody. (STAT5A 抗体 (pTyr694))

3 images

(1 reference)

产品编号 ABIN389668

发货至: 中国

Datasheet as PDF

抗原 See all STAT5A 抗体

STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
抗原表位
34

22

17

15

15

14

9

4

4

4

3

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr694
适用
181

96

69

22

8

7

6

5

3

3

3

1

1

1

1
人
宿主
162

21

2
兔
Compatible Secondaries
克隆类型
151

34
多克隆
标记
107

10

6

5

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

2

1
This STAT5A antibody is un-conjugated
应用范围
154

66

61

40

39

26

22

17

17

12

10

8

6

5

3

2

2

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This STAT5a Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y694 of human STAT5a.

克隆位点

RB5956

亚型

Ig Fraction

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anti-Signal Transducer and Activator of Transcription 5A (STAT5A) antibody
STAT5A 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 6E5 unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 583-794) antibody
STAT5A 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6D4 unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 1-794) antibody
STAT5A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 1-104) antibody
STAT5A 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1B12 unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 635-794) antibody
STAT5A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (C-Term) antibody
STAT5A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (pSer780) antibody
STAT5A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (pTyr694) antibody
STAT5A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 61-160) antibody
STAT5A 适用: 人, 小鼠, 大鼠, Cow WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 763-797), (C-Term) antibody
STAT5A 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB52392 unconjugated

应用备注

IF: 1:200. WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Moreira, Cabezón, Gromova, Gromov, Timmermans-Wielenga, Machado, Llombart-Bosch, Kroman, Rank, Celis: "Tissue proteomics of the human mammary gland: towards an abridged definition of the molecular phenotypes underlying epithelial normalcy." in: Molecular oncology, Vol. 4, Issue 6, pp. 539-61, (2010) (PubMed).
抗原

STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))

别名

STAT5a (STAT5A 产品)

别名

MGF antibody, STAT5 antibody, AA959963 antibody, Stat5 antibody, STAT5A/MGF antibody, STATA5 antibody, STAT5A antibody, stat5 antibody, stat5b antibody, signal transducer and activator of transcription 5A antibody, signal transducer and activator of transcription 5a antibody, STAT5A antibody, Stat5a antibody, stat5a antibody, LOC100348518 antibody, LOC100716811 antibody

背景

STAT5a is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this protein is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this protein in cells.

分子量

90647

基因ID

6776

NCBI登录号

NP_003143

UniProt

P42229

途径

JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation