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RAD9A 抗体 (pSer272)

RAD9A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7109 unconjugated
产品编号 ABIN389631
发货至: 中国
  • 抗原 See all RAD9A 抗体
    RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
    抗原表位
    • 22
    • 15
    • 15
    • 14
    • 10
    • 9
    • 8
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    • 6
    • 6
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    pSer272
    适用
    • 146
    • 48
    • 22
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    宿主
    • 158
    • 9
    • 1
    克隆类型
    • 159
    • 9
    多克隆
    标记
    • 69
    • 15
    • 13
    • 12
    • 10
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    • 3
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    • 3
    • 3
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    • 1
    • 1
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    This RAD9A antibody is un-conjugated
    应用范围
    • 136
    • 82
    • 54
    • 41
    • 40
    • 28
    • 12
    • 10
    • 9
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    Pr
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This RAD9 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S272 of human RAD9.
    克隆位点
    RB7109
    亚型
    Ig Fraction
    Top Product
    Discover our top product RAD9A Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:10~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Kelly, Davey: "Tousled-like kinase-dependent phosphorylation of Rad9 plays a role in cell cycle progression and G2/M checkpoint exit." in: PLoS ONE, Vol. 8, Issue 12, pp. e85859, (2013) (PubMed).

    Mohni, Dee, Smith, Schumacher, Weller: "Efficient herpes simplex virus 1 replication requires cellular ATR pathway proteins." in: Journal of virology, Vol. 87, Issue 1, pp. 531-42, (2012) (PubMed).

    Xu, Vaithiyalingam, Glick, Mordes, Chazin, Cortez: "The basic cleft of RPA70N binds multiple checkpoint proteins, including RAD9, to regulate ATR signaling." in: Molecular and cellular biology, Vol. 28, Issue 24, pp. 7345-53, (2008) (PubMed).

  • 抗原
    RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
    别名
    RAD9 (RAD9A 产品)
    别名
    RAD9 antibody, Rad9 antibody, rad9a antibody, MGC89062 antibody, XRad9 antibody, rad9 antibody, RAD9 checkpoint clamp component A antibody, RAD9 checkpoint clamp component B antibody, RAD9 checkpoint clamp component A L homeolog antibody, RAD9A antibody, Rad9a antibody, rad9a antibody, rad9b antibody, rad9a.L antibody
    背景
    Rad9 is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade.
    分子量
    42547
    基因ID
    5883
    NCBI登录号
    NP_001230153, NP_004575
    UniProt
    Q99638
    途径
    Positive Regulation of Response to DNA Damage Stimulus
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