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- 抗原 See all CDK2 抗体
- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
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抗原表位
- pThr160
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- B, Ha, M, Rat
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This Cdk2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T160 of human Cdk2.
- 克隆位点
- RB7342
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CDK2 Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Phosphorylation of CDK2 on threonine 160 influences silencing of sex chromosome during male meiosis." in: Biology of reproduction, Vol. 90, Issue 6, pp. 138, (2014) (PubMed).
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Phosphorylation of CDK2 on threonine 160 influences silencing of sex chromosome during male meiosis." in: Biology of reproduction, Vol. 90, Issue 6, pp. 138, (2014) (PubMed).
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- 抗原
- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
- 别名
- Cdk2 (CDK2 产品)
- 背景
- Cdk2 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
- 分子量
- 33930
- 基因ID
- 1017
- NCBI登录号
- NP_001789, NP_439892
- UniProt
- P24941
- 途径
- PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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