CDC25A 抗体 (pSer75)
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- 抗原 See all CDC25A 抗体
- CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
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抗原表位
- pSer75
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDC25A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This CDC25A Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S75 of human CDC25A.
- 克隆位点
- RB7853
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CDC25A Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Mangrove dolabrane-type of diterpenes tagalsins suppresses tumor growth via ROS-mediated apoptosis and ATM/ATR-Chk1/Chk2-regulated cell cycle arrest." in: International journal of cancer. Journal international du cancer, (2015) (PubMed).
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Mangrove dolabrane-type of diterpenes tagalsins suppresses tumor growth via ROS-mediated apoptosis and ATM/ATR-Chk1/Chk2-regulated cell cycle arrest." in: International journal of cancer. Journal international du cancer, (2015) (PubMed).
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- 抗原
- CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
- 别名
- CDC25A (CDC25A 产品)
- 别名
- cdc25a2 antibody, cdc25A antibody, sb:cb317 antibody, CDC25A2 antibody, D9Ertd393e antibody, cell division cycle 25A antibody, cell division cycle 25B antibody, cell division cycle 25A S homeolog antibody, CDC25A antibody, cdc25a antibody, cdc25b antibody, Cdc25a antibody, cdc25a.S antibody
- 背景
- CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 59087
- 基因ID
- 993
- NCBI登录号
- NP_001780, NP_963861
- UniProt
- P30304
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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