Caspase 9 抗体 (pSer196)
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- 抗原 See all Caspase 9 (CASP9) 抗体
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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抗原表位
- pSer196
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Caspase 9 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This Phospho-Caspase 9-S196 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S196 of human caspase 9.
- 克隆位点
- RB6898
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CASP9 Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Phosphorylation status of Akt and caspase-9 in gastric and colorectal carcinomas." in: International journal of clinical and experimental pathology, Vol. 7, Issue 6, pp. 3312-7, (2014) (PubMed).
: "Microenvironment mesenchymal cells protect ovarian cancer cell lines from apoptosis by inhibiting XIAP inactivation." in: Cell death & disease, Vol. 4, pp. e887, (2014) (PubMed).
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Phosphorylation status of Akt and caspase-9 in gastric and colorectal carcinomas." in: International journal of clinical and experimental pathology, Vol. 7, Issue 6, pp. 3312-7, (2014) (PubMed).
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- 抗原
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
- 别名
- Caspase 9 (CASP9 产品)
- 背景
- Caspase 9 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1, this step is thought to be one of the earliest in the caspase activation cascade.
- 分子量
- 46281
- 基因ID
- 842
- NCBI登录号
- NP_001220, NP_001264983, NP_127463
- UniProt
- P55211
- 途径
- MAPK Pathway, RTK signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
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