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IMMT 抗体 (AA 438-467)

IMMT 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20815 unconjugated
产品编号 ABIN389477
发货至: 中国
  • 抗原 See all IMMT 抗体
    IMMT (Inner Membrane Protein, Mitochondrial (IMMT))
    抗原表位
    • 15
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 438-467
    适用
    • 52
    • 26
    • 25
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 49
    • 3
    克隆类型
    • 50
    • 2
    多克隆
    标记
    • 22
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IMMT antibody is un-conjugated
    应用范围
    • 36
    • 15
    • 13
    • 13
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    M, Rat
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This IMMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-467 amino acids from the Central region of human IMMT.
    克隆位点
    RB20815
    亚型
    Ig Fraction
    Top Product
    Discover our top product IMMT Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Steffen, Vashisht, Wan, Jen, Claypool, Wohlschlegel, Koehler: "Rapid degradation of mutant SLC25A46 by the ubiquitin-proteasome system results in MFN1/2-mediated hyperfusion of mitochondria." in: Molecular biology of the cell, Vol. 28, Issue 5, pp. 600-612, (2017) (PubMed).

  • 抗原
    IMMT (Inner Membrane Protein, Mitochondrial (IMMT))
    别名
    IMMT (IMMT 产品)
    别名
    HMP antibody, MINOS2 antibody, P87 antibody, P87/89 antibody, P89 antibody, PIG52 antibody, 1700082C19Rik antibody, D830041H16Rik antibody, inner membrane mitochondrial protein antibody, inner membrane protein, mitochondrial antibody, IMMT antibody, Immt antibody
    背景
    Mitochondria are the center of cellular energy production and essential metabolic reactions. As double membrane-bound organelles, mitochondria from different species, tissues, and metabolic states are highly polymorphic in nature, yet exhibit common structural features. The ultrastructural variations in mitochondrial architecture occur mainly due to the differences in the amount and shape of cristae. Abundant cristae are found in mitochondria from tissues where energy demand is high. Analysis of the human heart mitochondrial proteome shows that mitofilin is one of the most abundant mitochondrial proteins. It appears to play an important role in the maintenance of cristae morphology.
    分子量
    83678
    基因ID
    10989
    NCBI登录号
    NP_001093639, NP_001093640, NP_006830
    UniProt
    Q16891
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