电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

INPP5D 抗体 (AA 770-796)

This anti-INPP5D antibody is a 兔 多克隆 antibody detecting INPP5D in WB. Suitable for 人.
产品编号 ABIN389359
发货至: 中国

Quick Overview for INPP5D 抗体 (AA 770-796) (ABIN389359)

抗原

See all INPP5D 抗体
INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))

适用

  • 84
  • 63
  • 42
  • 20
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 83
  • 2

克隆类型

  • 70
  • 15
多克隆

标记

  • 35
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This INPP5D antibody is un-conjugated

应用范围

  • 62
  • 23
  • 17
  • 7
  • 6
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)

克隆位点

RB17405
  • 抗原表位

    • 19
    • 18
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 770-796

    预测反应

    M, Rat

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This INPP5D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 770-796 amino acids from the Central region of human INPP5D.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))

    别名

    INPP5D

    背景

    INPP5D is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and it is a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival.

    分子量

    133292

    基因ID

    3635

    NCBI登录号

    NP_001017915, NP_005532

    UniProt

    Q92835

    途径

    TCR Signaling, BCR Signaling, Warburg Effect
You are here:
Chat with us!