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INPP5D 抗体 (AA 770-796)

INPP5D 适用: 人 WB 宿主: 兔 Polyclonal RB17405 unconjugated
产品编号 ABIN389359
发货至: 中国
  • 抗原 See all INPP5D 抗体
    INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
    抗原表位
    • 18
    • 18
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 770-796
    适用
    • 86
    • 63
    • 42
    • 20
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 85
    • 2
    克隆类型
    • 75
    • 12
    多克隆
    标记
    • 30
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This INPP5D antibody is un-conjugated
    应用范围
    • 57
    • 20
    • 16
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    M, Rat
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This INPP5D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 770-796 amino acids from the Central region of human INPP5D.
    克隆位点
    RB17405
    亚型
    Ig Fraction
    Top Product
    Discover our top product INPP5D Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
    别名
    INPP5D (INPP5D 产品)
    别名
    INPP5D antibody, 256.t00004 antibody, 13.t00027 antibody, ship antibody, ship1 antibody, AI323613 antibody, SHIP antibody, SHIP-1 antibody, SHIP1 antibody, s-SHIP antibody, SIP-145 antibody, hp51CN antibody, inositol polyphosphate-5-phosphatase D antibody, phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 antibody, inositol polyphosphate 5-phosphatase antibody, inositol polyphosphate-5-phosphatase D L homeolog antibody, INPP5D antibody, LOC100446045 antibody, inpp5d antibody, EHI_159880 antibody, EHI_153490 antibody, inpp5d.L antibody, LOC100380693 antibody, Inpp5d antibody
    背景
    INPP5D is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and it is a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival.
    分子量
    133292
    基因ID
    3635
    NCBI登录号
    NP_001017915, NP_005532
    UniProt
    Q92835
    途径
    TCR Signaling, BCR Signaling, Warburg Effect
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