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- 抗原 See all PFDN6 抗体
- PFDN6 (Prefoldin Subunit 6 (PFDN6))
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抗原表位
- AA 6-34, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PFDN6 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- B, M
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This PFDN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human PFDN6.
- 克隆位点
- RB17559
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PFDN6 Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Prefoldin protects neuronal cells from polyglutamine toxicity by preventing aggregation formation." in: The Journal of biological chemistry, Vol. 288, Issue 27, pp. 19958-72, (2013) (PubMed).
: "Prefoldin plays a role as a clearance factor in preventing proteasome inhibitor-induced protein aggregation." in: The Journal of biological chemistry, Vol. 288, Issue 39, pp. 27764-76, (2013) (PubMed).
: "Prefoldin subunits are protected from ubiquitin-proteasome system-mediated degradation by forming complex with other constituent subunits." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19191-203, (2011) (PubMed).
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Prefoldin protects neuronal cells from polyglutamine toxicity by preventing aggregation formation." in: The Journal of biological chemistry, Vol. 288, Issue 27, pp. 19958-72, (2013) (PubMed).
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- 抗原
- PFDN6 (Prefoldin Subunit 6 (PFDN6))
- 别名
- PFDN6 (PFDN6 产品)
- 别名
- hke2 antibody, ke-2 antibody, pfd6 antibody, h2-ke2 antibody, pfdn6a antibody, 23.m05913 antibody, H-2Ke2 antibody, Ke-2 antibody, Pfdn6 antibody, H2-KE2 antibody, HKE2 antibody, KE-2 antibody, PFD6 antibody, zgc:66282 antibody, pfdn6 antibody, pfdn6b antibody, Ke2 antibody, prefoldin subunit 6 S homeolog antibody, prefoldin subunit 6 (predicted) antibody, prefoldin subunit 6 antibody, prefoldin subunit 6 L homeolog antibody, pfdn6.S antibody, SPAC3A11.13 antibody, BBOV_IV004800 antibody, AOR_1_2254174 antibody, CMU_042830 antibody, pfdn6 antibody, Pfdn6 antibody, PFDN6 antibody, pfdn6.L antibody
- 背景
- PFDN6 binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. This protein also binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
- 分子量
- 14583
- 基因ID
- 10471
- NCBI登录号
- NP_001172110, NP_001252524, NP_001252525, NP_055075
- UniProt
- O15212
- 途径
- Unfolded Protein Response
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