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SNURF 抗体 (AA 4-32)

SNURF 适用: 人 宿主: 兔 Polyclonal RB17346 unconjugated
产品编号 ABIN389318
发货至: 中国
  • 抗原 See all SNURF 抗体
    SNURF (SNRPN Upstream Reading Frame (SNURF))
    抗原表位
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 4-32
    适用
    宿主
    • 3
    • 2
    克隆类型
    • 5
    多克隆
    标记
    • 5
    This SNURF antibody is un-conjugated
    应用范围
    请咨询
    预测反应
    B, M, Rb
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This SNURF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 amino acids from the Central region of human SNURF.
    克隆位点
    RB17346
    亚型
    Ig Fraction
    Top Product
    Discover our top product SNURF Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    SNURF (SNRPN Upstream Reading Frame (SNURF))
    别名
    SNURF (SNURF 产品)
    别名
    2410045I01Rik antibody, Snrpn antibody, SNRPN upstream reading frame antibody, small nuclear ribonucleoprotein polypeptide N antibody, SNURF antibody, SNRPN antibody, Snurf antibody
    背景
    SNURF is a highly basic protein localized to the nucleus. The evolutionarily constrained open reading frame of its gene is found on a bicistronic transcript which has a downstream ORF encoding the small nuclear ribonucleoprotein polypeptide N. The upstream coding region utilizes the first three exons of the transcript, a region that has been identified as an imprinting center. Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated, monocistronic transcript. Alternative splicing or deletion caused by a translocation event in the 5' UTR or coding region of this gene leads to Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. The function of this protein is not yet known.
    分子量
    8412
    基因ID
    8926
    NCBI登录号
    NP_005669, NP_073715
    UniProt
    Q9Y675
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