Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
预测反应
M
纯化方法
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
免疫原
This ZIC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 amino acids from the N-terminal region of human ZIC3.
HTX antibody, HTX1 antibody, VACTERLX antibody, ZNF203 antibody, RGD1561261 antibody, zic3-A antibody, Bn antibody, Zic family member 3 antibody, Zic family member 3 S homeolog antibody, zinc finger protein of the cerebellum 3 antibody, ZIC3 antibody, Zic3 antibody, zic3.S antibody
背景
ZIC3 is a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in the gene encoding ZIC3 cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs.