LGR5 抗体 (AA 443-473)
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- 抗原 See all LGR5 抗体
- LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
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抗原表位
- AA 443-473
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LGR5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- B
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This LGR5 (GPR49) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 443-473 amino acids from the Central region of human LGR5 (GPR49).
- 克隆位点
- RB14555
- 亚型
- Ig Fraction
- Top Product
- Discover our top product LGR5 Primary Antibody
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- 应用备注
- WB: 1:1000. WB: 1:1000. IHC: 1:100. IHC-P: 1:10~50. FC: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Multiple roles of integrin-linked kinase in epidermal development, maturation and pigmentation revealed by molecular profiling." in: PLoS ONE, Vol. 7, Issue 5, pp. e36704, (2012) (PubMed).
: "LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell lines." in: PLoS ONE, Vol. 6, Issue 7, pp. e22733, (2011) (PubMed).
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Multiple roles of integrin-linked kinase in epidermal development, maturation and pigmentation revealed by molecular profiling." in: PLoS ONE, Vol. 7, Issue 5, pp. e36704, (2012) (PubMed).
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- 抗原
- LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
- 别名
- LGR5 (GPR49) (LGR5 产品)
- 别名
- lgr5-a antibody, lgr5a antibody, FEX antibody, Gpr49 antibody, GPR49 antibody, GPR67 antibody, GRP49 antibody, HG38 antibody, leucine-rich repeat containing G protein-coupled receptor 5 L homeolog antibody, leucine rich repeat containing G protein coupled receptor 5 antibody, leucine rich repeat containing G protein-coupled receptor 5 antibody, lgr5.L antibody, Lgr5 antibody, LGR5 antibody
- 背景
- LGR5/GPR49 is an orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues.
- 分子量
- 99998
- 基因ID
- 8549
- NCBI登录号
- NP_001264155, NP_003658
- UniProt
- O75473
- 途径
- WNT signaling
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