LGR5 抗体 (AA 689-719)
(10 references)-
- 抗原 See all LGR5 抗体
- LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
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抗原表位
- AA 689-719
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LGR5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This LGR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 689-719 amino acids from human LGR5.
- 克隆位点
- RB14211
- 亚型
- IgG
- Top Product
- Discover our top product LGR5 Primary Antibody
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anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 810-907) antibody
LGR5 适用: 人, 小鼠 WB, FACS, ELISA, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 443-473) antibodyLGR5 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB14555 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 22-178) antibodyLGR5 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2B5B9 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 689-719) antibodyLGR5 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 443-473) antibodyLGR5 适用: 人 WB, FACS, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 250-550) antibodyLGR5 适用: 人, 小鼠 WB, FACS, IHC, IF, IP 宿主: 小鼠 Monoclonal 2A2 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (Cytoplasmic Domain) antibodyLGR5 适用: 人 IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 824-907) antibodyLGR5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 241-352) antibodyLGR5 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) antibodyLGR5 适用: 人 WB, FACS, ELISA 宿主: 兔 Monoclonal 4H8 unconjugated Recombinant Antibody
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- 应用备注
- WB: 1:1000. IF: 1:100. FC: 1:25
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze-thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
- 有效期
- 6 months
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: "Long-term culture of genome-stable bipotent stem cells from adult human liver. ..." in: Cell, Vol. 160, Issue 1-2, pp. 299-312, (2015) (PubMed).
: "The effectiveness of an anti-human IL-6 receptor monoclonal antibody combined with chemotherapy to target colon cancer stem-like cells." in: International journal of oncology, Vol. 46, Issue 4, pp. 1551-9, (2015) (PubMed).
: "Characterization of Three-Dimensional Retinal Tissue Derived from Human Embryonic Stem Cells in Adherent Monolayer Cultures." in: Stem cells and development, Vol. 24, Issue 23, pp. 2778-95, (2015) (PubMed).
: "ERBB3 Positively Correlates with Intestinal Stem Cell Markers but Marks a Distinct Non Proliferative Cell Population in Colorectal Cancer." in: PLoS ONE, Vol. 10, Issue 9, pp. e0138336, (2015) (PubMed).
: "LGR5 is a promising biomarker for patients with stage I and II gastric cancer." in: Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, Vol. 25, Issue 1, pp. 79-89, (2013) (PubMed).
: "Intestinal stem cell marker LGR5 expression during gastric carcinogenesis." in: World journal of gastroenterology : WJG, Vol. 19, Issue 46, pp. 8714-21, (2013) (PubMed).
: "Transcription factor Oct1 is a somatic and cancer stem cell determinant." in: PLoS genetics, Vol. 8, Issue 11, pp. e1003048, (2012) (PubMed).
: "Multiple roles of integrin-linked kinase in epidermal development, maturation and pigmentation revealed by molecular profiling." in: PLoS ONE, Vol. 7, Issue 5, pp. e36704, (2012) (PubMed).
: "Significance of Lgr5(+ve) cancer stem cells in the colon and rectum." in: Annals of surgical oncology, Vol. 18, Issue 4, pp. 1166-74, (2011) (PubMed).
: "Stable expression of neurogenin 1 induces LGR5, a novel stem cell marker, in an immortalized human neural stem cell line HB1.F3." in: Cellular and molecular neurobiology, Vol. 30, Issue 3, pp. 415-26, (2010) (PubMed).
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: "Long-term culture of genome-stable bipotent stem cells from adult human liver. ..." in: Cell, Vol. 160, Issue 1-2, pp. 299-312, (2015) (PubMed).
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- 抗原
- LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
- 别名
- LGR5/GPR49 (LGR5 产品)
- 别名
- lgr5-a antibody, lgr5a antibody, FEX antibody, Gpr49 antibody, GPR49 antibody, GPR67 antibody, GRP49 antibody, HG38 antibody, leucine-rich repeat containing G protein-coupled receptor 5 L homeolog antibody, leucine rich repeat containing G protein coupled receptor 5 antibody, leucine rich repeat containing G protein-coupled receptor 5 antibody, lgr5.L antibody, Lgr5 antibody, LGR5 antibody
- 背景
- LGR5/GPR49 is an orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues. Stem cell marker of the intestinal epithelium and the hair follicle. Target gene of Wnt signaling. Expressed in skeletal muscle, placenta, spinal cord, and various region of brain. Expressed at the base of crypts in colonic and small mucosa stem cells. In premalignant cancer expression is not restricted to the cript base. Overexpressed in cancers of the ovary, colon and liver.
- 分子量
- 99998
- 基因ID
- 8549
- NCBI登录号
- NP_001264155, NP_003658
- UniProt
- O75473
- 途径
- WNT signaling
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