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- 抗原 See all PPT1 抗体
- PPT1 (Palmitoyl-Protein Thioesterase 1 (PPT1))
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抗原表位
- AA 269-300, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PPT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- Pr
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This PPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-300 amino acids from the C-terminal region of human PPT1.
- 克隆位点
- RB4707
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PPT1 Primary Antibody
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anti-Palmitoyl-Protein Thioesterase 1 (PPT1) (AA 100-306) antibody
PPT1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1F10 unconjugated
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) (AA 1-306) antibodyPPT1 适用: 人 WB, IHC (p), FACS 宿主: 小鼠 Monoclonal 1117CT11-2-1-4 unconjugated
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) antibodyPPT1 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 小鼠 Monoclonal 10G4 unconjugated
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) (AA 1-306) antibodyPPT1 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) (AA 100-306) antibodyPPT1 适用: 人, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1A10 unconjugated
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) (AA 188-290) antibodyPPT1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) (AA 28-279) antibodyPPT1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) (AA 100-258) antibodyPPT1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) (AA 191-224), (C-Term) antibodyPPT1 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) antibodyPPT1 适用: 人, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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- 抗原
- PPT1 (Palmitoyl-Protein Thioesterase 1 (PPT1))
- 别名
- PPT1 (PPT1 产品)
- 别名
- CLN1 antibody, INCL antibody, PPT antibody, 9530043G02Rik antibody, AA960502 antibody, C77813 antibody, D4Ertd184e antibody, Ppt antibody, wu:fj17f04 antibody, zgc:63969 antibody, PPT-1 antibody, ppt1 antibody, palmitoyl-protein thioesterase 1 antibody, Palmitoyl-protein thioesterase 1 antibody, palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) antibody, palmitoyl-protein thioesterase 1 L homeolog antibody, PPT1 antibody, MGYG_00692 antibody, Ppt1 antibody, ppt-1 antibody, ppt1 antibody, ppt1.L antibody
- 背景
- Palmitoyl-protein thioesterase-1 (PPT1) is a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. Mutations in PPT1 have been found to cause the infantile form of neuronal ceroid lipofuscinosis (INCL), and an animal model has been developed.1 The deduced PPT2 protein contains 302 amino acids, including a 27-amino acid leader peptide, a sequence motif characteristic of many thioesterases and lipases, and 5 potential N-linked glycosylation sites.2 PPT2 shares 18 % amino acid identity with PPT1. Northern blot analysis detected a predominant 2.0-kb PPT2 transcript in the human tissues examined, with the highest expression in skeletal muscle, variable amounts of 2.8- and 7.0-kb transcripts were also observed. Recombinant PPT2, like PPT1, possesses thioesterase activity and localizes to the lysosome. Since PPT2 could not substitute for PPT1 in correcting the metabolic defect in INCL cells and was unable to remove palmitate groups from palmitoylated proteins that are routinely used as substrates for PPT1it has been postulated that PPT2 possesses a different substrate specificity than PPT1.
- 分子量
- 34193
- 基因ID
- 5538
- NCBI登录号
- NP_000301, NP_001136076
- UniProt
- P50897
- 途径
- SARS-CoV-2 Protein Interactome
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