GGPS1 抗体 (C-Term)
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- 抗原 See all GGPS1 抗体
- GGPS1 (Geranylgeranyl Diphosphate Synthase 1 (GGPS1))
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抗原表位
- AA 270-300, C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GGPS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This GGPS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-300 amino acids from the C-terminal region of human GGPS1.
- 克隆位点
- RB4789
- 亚型
- Ig Fraction
- Top Product
- Discover our top product GGPS1 Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Quantitative proteomics analysis of inborn errors of cholesterol synthesis: identification of altered metabolic pathways in DHCR7 and SC5D deficiency." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 7, pp. 1461-75, (2010) (PubMed).
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Quantitative proteomics analysis of inborn errors of cholesterol synthesis: identification of altered metabolic pathways in DHCR7 and SC5D deficiency." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 7, pp. 1461-75, (2010) (PubMed).
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- 抗原
- GGPS1 (Geranylgeranyl Diphosphate Synthase 1 (GGPS1))
- 别名
- GGPS1 (GGPS1 产品)
- 别名
- geranylgeranyl pyrophosphate synthase 1 antibody, DDBDRAFT_0192027 antibody, DDBDRAFT_0233098 antibody, DDB_0192027 antibody, DDB_0233098 antibody, GGPPS antibody, GGPPS1 antibody, 1810026C22Rik antibody, 9530089B04Rik antibody, AI843169 antibody, C79210 antibody, Crlf3 antibody, rGGPS1a antibody, rGGPS1a1 antibody, rGGPS1a2 antibody, rGGPS1a3 antibody, fb05f09 antibody, qm antibody, wu:fb05f09 antibody, zgc:101591 antibody, zgc:56514 antibody, geranylgeranyl pyrophosphate synthase 1 antibody, geranylgeranyl pyrophosphate synthetase antibody, geranyl pyrophosphate synthase antibody, geranylgeranyl pyrophosphate synthase,chloroplastic antibody, geranylgeranyl diphosphate synthase 1 antibody, geranylgeranyl diphosphate synthase 1 L homeolog antibody, GGPS1 antibody, gGPS1 antibody, ggps1 antibody, Ggps1 antibody, ggps1.L antibody
- 背景
- Geranylgeranyl diphosphate (GGPP) synthase (GGPS) catalyzes the synthesis of GGPP, a molecule responsible for the C20-prenylation of protein and for the regulation of a nuclear hormone receptor. The deduced 300-amino acid human protein contains 5 conserved domains consistent with prenyltransferases. Recombinant GGPS shows enzymatic properties associated with the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. Mouse GGPS is regulated in several tissues in obesity and is induced during adipocyte differentiation. GGPS is increased 5- to 20-fold in skeletal muscle, liver, and fat of ob/ob mice. Western blot analysis detects a 2-fold overexpression of protein in muscle and fat but not in liver. Differentiation of mouse fibroblasts into adipocytes induces GGPS expression more than 20-fold.
- 分子量
- 34871
- 基因ID
- 9453
- NCBI登录号
- NP_001032354
- UniProt
- O95749
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