FDPS 抗体 (AA 389-419)
(6 references)-
- 抗原 See all FDPS 抗体
- FDPS (Farnesyl Diphosphate Synthase (FDPS))
-
抗原表位
- AA 389-419
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This FDPS antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This FDPS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-419 amino acids from the center region of human FDPS.
- 克隆位点
- RB04786
- 亚型
- Ig Fraction
- Top Product
- Discover our top product FDPS Primary Antibody
-
anti-Farnesyl Diphosphate Synthase (FDPS) antibody
FDPS 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Farnesyl Diphosphate Synthase (FDPS) (AA 1-419) antibodyFDPS 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Farnesyl Diphosphate Synthase (FDPS) (AA 1-419) antibodyFDPS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Farnesyl Diphosphate Synthase (FDPS) (AA 120-419) antibodyFDPS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Farnesyl Diphosphate Synthase (FDPS) (AA 82-112), (N-Term) antibodyFDPS 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB4783-4784 unconjugated
anti-Farnesyl Diphosphate Synthase (FDPS) antibodyFDPS 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Farnesyl Diphosphate Synthase (FDPS) (AA 1-419) antibodyFDPS 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Farnesyl Diphosphate Synthase (FDPS) antibodyFDPS 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 1049CT13-1-4 unconjugated
anti-Farnesyl Diphosphate Synthase (FDPS) (AA 1-419) antibodyFDPS 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Farnesyl Diphosphate Synthase (FDPS) (AA 320-419) antibodyFDPS 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3A6 unconjugated
-
- 应用备注
- WB: 1:1000. IHC-P: 1:10~50
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
-
-
: "Liposome encapsulated zoledronate favours M1-like behaviour in murine macrophages cultured with soluble factors from breast cancer cells." in: BMC cancer, Vol. 15, pp. 4, (2015) (PubMed).
: "Altered expression of farnesyl pyrophosphate synthase in prostate cancer: evidence for a role of the mevalonate pathway in disease progression?" in: World journal of urology, Vol. 31, Issue 2, pp. 345-50, (2013) (PubMed).
: "5-Aza-2'-deoxycytidine induced growth inhibition of leukemia cells through modulating endogenous cholesterol biosynthesis." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 7, pp. M111.016915, (2012) (PubMed).
: "Sterol-regulatory-element-binding protein 2 and nuclear factor Y control human farnesyl diphosphate synthase expression and affect cell proliferation in hepatoblastoma cells." in: The Biochemical journal, Vol. 429, Issue 2, pp. 347-57, (2010) (PubMed).
: "Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells." in: Biochemical pharmacology, Vol. 79, Issue 5, pp. 777-83, (2010) (PubMed).
: "Reduced expression of the mevalonate pathway enzyme farnesyl pyrophosphate synthase unveils recognition of tumor cells by Vgamma9Vdelta2 T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 12, pp. 8118-24, (2009) (PubMed).
-
: "Liposome encapsulated zoledronate favours M1-like behaviour in murine macrophages cultured with soluble factors from breast cancer cells." in: BMC cancer, Vol. 15, pp. 4, (2015) (PubMed).
-
- 抗原
- FDPS (Farnesyl Diphosphate Synthase (FDPS))
- 别名
- FDPS (FDPS 产品)
- 别名
- CG12389 antibody, DmFPPS antibody, DmFPPSase antibody, DmFPS antibody, Dmel\\CG12389 antibody, FPS antibody, fpps antibody, fps antibody, l(2)k06103 antibody, v(2)k03514 antibody, NCU01175.1 antibody, 16.m00760 antibody, DDBDRAFT_0206220 antibody, DDBDRAFT_0215017 antibody, DDB_0206220 antibody, DDB_0215017 antibody, FPPS antibody, Ac2-125 antibody, (2E antibody, 6030492I17Rik antibody, AI256750 antibody, Fdpsl1 antibody, mKIAA1293 antibody, Farnesyl pyrophosphate synthase antibody, farnesyl diphosphate synthase antibody, farnesyl diphosphate synthase L homeolog antibody, farnesyl pyrophosphate synthase antibody, farnesyl pyrophosphate synthetase antibody, farnesyl-pyrophosphate synthetase antibody, FDP synthase antibody, Farnesyl pyrophosphate synthetase antibody, farnesyl diphosphate synthetase antibody, farnesyl pyrophosphate synthase 1 antibody, Fpps antibody, fdps antibody, fdps.L antibody, MGG_08649 antibody, TP03_0857 antibody, Tb09.160.4300 antibody, fpp antibody, BBOV_I000120 antibody, fps antibody, fpps antibody, FDPS antibody, Fdps antibody, fps1 antibody
- 背景
- The isoprene biosynthetic pathway supply the cell with cholesterol, ubiquinone, and various nonsterol metabolites. The farnesylpyrophosphate synthetase enzyme catalyzes the formation of geranyl and farnesylpyrophosphate from isopentenylpyrophosphate and dimethylallyl pyrophosphate. Analysis of FDPS activity and protein in rat liver, accompanied by immunofluorescence and immunoelectron microscopy studies, demonstrated that FDPS is predominantly localized in peroxisomes.1 Liver tissue from patients with the peroxisomal deficiency diseases Zellweger syndrome and neonatal adrenoleukodystrophy exhibit diminished activities of FDPS and subsequent isoprenoid synthesis.
- 分子量
- 48275
- 基因ID
- 2224
- NCBI登录号
- NP_001129293, NP_001129294, NP_001229753, NP_001229754, NP_001995
- UniProt
- P14324
- 途径
- Regulation of Muscle Cell Differentiation
-
