FDFT1 抗体 (AA 140-170)
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- 抗原 See all FDFT1 抗体
- FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))
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抗原表位
- AA 140-170
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FDFT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-170 amino acids from the Central region of human FDFT1.
- 克隆位点
- RB4781-4782
- 亚型
- Ig Fraction
- Top Product
- Discover our top product FDFT1 Primary Antibody
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- 应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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5-Aza-2'-deoxycytidine induced growth inhibition of leukemia cells through modulating endogenous cholesterol biosynthesis." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 7, pp. M111.016915, (2012) (PubMed).
: "Proteomic analysis of doxorubicin-induced changes in the proteome of HepG2cells combining 2-D DIGE and LC-MS/MS approaches." in: Proteomics, Vol. 10, Issue 1, pp. 99-114, (2010) (PubMed).
: "Docosahexaenoic acid activates some SREBP-2 targets independent of cholesterol and ER stress in SW620 colon cancer cells." in: Lipids, Vol. 44, Issue 8, pp. 673-83, (2009) (PubMed).
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5-Aza-2'-deoxycytidine induced growth inhibition of leukemia cells through modulating endogenous cholesterol biosynthesis." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 7, pp. M111.016915, (2012) (PubMed).
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- 抗原
- FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))
- 别名
- FDFT1 (FDFT1 产品)
- 别名
- FDFT1 antibody, DKFZp459C1712 antibody, SQS antibody, SS antibody, DGPT antibody, ERG9 antibody, fdft1 antibody, farnesyl-diphosphate farnesyltransferase 1 antibody, squalene synthase antibody, farnesyl diphosphate farnesyl transferase 1 antibody, FDFT1 antibody, fdft1 antibody, LOC100560926 antibody, Fdft1 antibody
- 背景
- FDFT1 catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.
- 分子量
- 48115
- 基因ID
- 2222
- NCBI登录号
- NP_004453
- UniProt
- P37268
- 途径
- Regulation of Lipid Metabolism by PPARalpha
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