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EPS15L1 抗体 (N-Term)

EPS15L1 适用: 人 WB 宿主: 兔 Polyclonal RB4395 unconjugated
产品编号 ABIN388934
发货至: 中国
  • 抗原 See all EPS15L1 products
    EPS15L1 (Epidermal Growth Factor Receptor Pathway Substrate 15-Like 1 (EPS15L1))
    抗原表位
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 186-216, N-Term
    适用
    • 31
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 31
    克隆类型
    • 30
    多克隆
    标记
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EPS15L1 antibody is un-conjugated
    应用范围
    • 24
    • 16
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This EPS15R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-216 amino acids from the N-terminal region of human EPS15R.
    克隆位点
    RB4395
    亚型
    Ig Fraction
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    EPS15L1 (Epidermal Growth Factor Receptor Pathway Substrate 15-Like 1 (EPS15L1))
    别名
    EPS15R (EPS15L1 产品)
    别名
    Eps15R antibody, XEps15R antibody, EPS15R antibody, 9830147J04Rik antibody, AI593686 antibody, Eps15-rs antibody, epidermal growth factor receptor pathway substrate 15-like 1 S homeolog antibody, epidermal growth factor receptor pathway substrate 15 like 1 antibody, epidermal growth factor receptor pathway substrate 15-like 1 antibody, eps15l1.S antibody, EPS15L1 antibody, Eps15l1 antibody
    背景
    Ubiquitin is a 76 amino acid highly conserved eukaryotic polypeptide that selectively marks cellular proteins for proteolytic degradation by the 26S proteasome. The process of target selection, covalent attachment and shuttle to the 26S proteasome is a vital means of regulating the concentrations of key regulatory proteins in the cell by limiting their lifespans. Polyubiquitination is a common feature of this modification. Serial steps for modification include the activation of ubiquitin, an ATP-dependent formation of a thioester bond between ubiquitin and the enzyme E1, transfer by transacylation of ubiquitin from E1 to the ubiquitin conjugating enzyme E2, and covalent linkage to the target protein directly by E2 or via E3 ligase enzyme. Deubiquitination enzymes also exist to reverse the marking of protein substrates. Posttranslational tagging by Ub is involved in a multitude of cellular processes, including the cell cycle, cell growth and differentiation, embryogenesis, apoptosis, signal transduction, DNA repair, regulation of transcription and DNA replication, transmembrane transport, stress responses, the immune response, and nervous system functions.
    分子量
    94255
    基因ID
    58513
    NCBI登录号
    NP_001245303, NP_001245304, NP_001245305, NP_067058
    UniProt
    Q9UBC2
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