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USP25 抗体 (N-Term)

USP25 适用: 人 WB 宿主: 兔 Polyclonal RB4364 unconjugated
产品编号 ABIN388917
发货至: 中国
  • 抗原 See all USP25 抗体
    USP25 (Ubiquitin Specific Peptidase 25 (USP25))
    抗原表位
    • 8
    • 7
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 133-163, N-Term
    适用
    • 28
    • 10
    • 3
    宿主
    • 27
    • 1
    克隆类型
    • 27
    • 1
    多克隆
    标记
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    This USP25 antibody is un-conjugated
    应用范围
    • 23
    • 21
    • 13
    • 3
    • 2
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This USP25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-163 amino acids from the N-terminal region of human USP25.
    克隆位点
    RB4364
    亚型
    Ig Fraction
    Top Product
    Discover our top product USP25 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    USP25 (Ubiquitin Specific Peptidase 25 (USP25))
    别名
    USP25 (USP25 产品)
    别名
    USP25 antibody, zgc:55791 antibody, wu:fi33c05 antibody, wu:fo67e06 antibody, wu:fp97a04 antibody, usp25 antibody, MGC81666 antibody, usp21 antibody, USP21 antibody, ubiquitin specific peptidase 25 antibody, universal stress protein UspA antibody, ubiquitin specific peptidase 25 L homeolog antibody, USP25 antibody, RR_RS03930 antibody, usp25 antibody, usp25.L antibody, Usp25 antibody
    背景
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
    分子量
    122218
    基因ID
    29761
    NCBI登录号
    NP_037528
    UniProt
    Q9UHP3
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