(2 references)-
- 抗原 See all USP22 抗体
- USP22 (Ubiquitin Specific Peptidase 22 (USP22))
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抗原表位
- AA 1-30, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This USP22 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This USP22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human USP22.
- 克隆位点
- RB4357
- 亚型
- Ig Fraction
- Top Product
- Discover our top product USP22 Primary Antibody
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anti-Ubiquitin Specific Peptidase 22 (USP22) (Middle Region) antibody
USP22 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, Cow, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 22 (USP22) (AA 330-478), (C-Term) antibodyUSP22 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 22 (USP22) (AA 351-380), (C-Term) antibodyUSP22 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4359 unconjugated
anti-Ubiquitin Specific Peptidase 22 (USP22) (AA 121-220) antibodyUSP22 适用: 人, 大鼠, 非洲爪蟾 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 22 (USP22) antibodyUSP22 适用: 人 WB 宿主: 小鼠 Monoclonal 4C1 unconjugated
anti-Ubiquitin Specific Peptidase 22 (USP22) (AA 216-265) antibodyUSP22 适用: 人, 大鼠, 小鼠, 非洲爪蟾, 犬, 豚鼠, 马, Cow, 兔, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 22 (USP22) (AA 72-121) antibodyUSP22 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 22 (USP22) (C-Term) antibodyUSP22 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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: "Deubiquitinating enzyme USP22 positively regulates c-Myc stability and tumorigenic activity in mammalian and breast cancer cells." in: Journal of cellular physiology, Vol. 232, Issue 12, pp. 3664-3676, (2017) (PubMed).
: "Ubiquitin-specific protease 22 (USP22) positively regulates RCAN1 protein levels through RCAN1 de-ubiquitination." in: Journal of cellular physiology, Vol. 230, Issue 7, pp. 1651-60, (2015) (PubMed).
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: "Deubiquitinating enzyme USP22 positively regulates c-Myc stability and tumorigenic activity in mammalian and breast cancer cells." in: Journal of cellular physiology, Vol. 232, Issue 12, pp. 3664-3676, (2017) (PubMed).
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- 抗原
- USP22 (Ubiquitin Specific Peptidase 22 (USP22))
- 别名
- USP22 (USP22 产品)
- 别名
- USP3L antibody, AI427806 antibody, zgc:136342 antibody, usp22 antibody, usp22 b antibody, usp22-B antibody, usp22-a antibody, usp3l antibody, ubiquitin specific peptidase 22 antibody, ubiquitin specific peptidase 22 S homeolog antibody, USP22 antibody, Usp22 antibody, usp22 antibody, usp22.S antibody
- 背景
- Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
- 分子量
- 59961
- 基因ID
- 23326
- NCBI登录号
- NP_056091
- UniProt
- Q9UPT9
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