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USP15 抗体 (N-Term)

USP15 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB4337 unconjugated
产品编号 ABIN388904
发货至: 中国
  • 抗原 See all USP15 抗体
    USP15 (Ubiquitin Specific Peptidase 15 (USP15))
    抗原表位
    • 9
    • 7
    • 7
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-180, N-Term
    适用
    • 49
    • 27
    • 9
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 47
    • 1
    • 1
    克隆类型
    • 47
    • 1
    多克隆
    标记
    • 27
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This USP15 antibody is un-conjugated
    应用范围
    • 37
    • 29
    • 9
    • 8
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This USP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the N-terminal region of human USP15.
    克隆位点
    RB4337
    亚型
    Ig Fraction
    Top Product
    Discover our top product USP15 Primary Antibody
  • 应用备注
    IF: 1:25. WB: 1:1000. WB: 1:1000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:2500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    USP15 (Ubiquitin Specific Peptidase 15 (USP15))
    别名
    USP15 (USP15 产品)
    别名
    USP15 antibody, UNP antibody, UNPH-2 antibody, UNPH4 antibody, 4921514G19Rik antibody, AI327321 antibody, E430033I05Rik antibody, Gcap18 antibody, mKIAA0529 antibody, Ubp109 antibody, ubiquitin specific peptidase 15 antibody, universal stress protein UspA antibody, ubiquitin carboxyl-terminal hydrolase 15 antibody, USP15 antibody, RR_RS05795 antibody, LOC100090554 antibody, usp15 antibody, Usp15 antibody
    背景
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
    分子量
    112419
    基因ID
    9958
    NCBI登录号
    NP_001239007, NP_001239008, NP_006304
    UniProt
    Q9Y4E8
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