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USP12 抗体 (N-Term)

USP12 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB4297 unconjugated
产品编号 ABIN388898
发货至: 中国
  • 抗原 See all USP12 抗体
    USP12 (Ubiquitin Specific Peptidase 12 (USP12))
    抗原表位
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 5-35, N-Term
    适用
    • 42
    • 36
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 50
    • 4
    克隆类型
    • 53
    • 1
    多克隆
    标记
    • 23
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This USP12 antibody is un-conjugated
    应用范围
    • 42
    • 34
    • 9
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    X, B
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This USP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-35 amino acids from the N-terminal region of human USP12.
    克隆位点
    RB4297
    亚型
    Ig Fraction
    Top Product
    Discover our top product USP12 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    USP12 (Ubiquitin Specific Peptidase 12 (USP12))
    别名
    USP12 (USP12 产品)
    别名
    UBH1 antibody, USP12L1 antibody, usp12 antibody, USP12P1 antibody, sb:eu882 antibody, wu:fi09d12 antibody, Ubh1 antibody, ubh1 antibody, usp12l1 antibody, ubiquitin specific peptidase 12 antibody, ubiquitin specific peptidase 12a antibody, ubiquitin specific peptidase 12 L homeolog antibody, ubiquitin specific peptidase 12 S homeolog antibody, USP12 antibody, usp12 antibody, Usp12 antibody, usp12a antibody, usp12.L antibody, usp12.S antibody
    背景
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
    分子量
    42858
    基因ID
    219333
    NCBI登录号
    NP_872294
    UniProt
    O75317
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