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UBE2L6 抗体 (C-Term)

UBE2L6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4157 unconjugated
产品编号 ABIN388854
发货至: 中国
  • 抗原 See all UBE2L6 抗体
    UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
    抗原表位
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 123-153, C-Term
    适用
    • 35
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 30
    • 6
    克隆类型
    • 33
    • 3
    多克隆
    标记
    • 21
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBE2L6 antibody is un-conjugated
    应用范围
    • 24
    • 16
    • 10
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This UBE2L6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-153 amino acids from the C-terminal region of human UBE2L6.
    克隆位点
    RB4157
    亚型
    Ig Fraction
    Top Product
    Discover our top product UBE2L6 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Zhao, Sridharan, Chen, Baker, Wang, Krug: "Influenza B virus non-structural protein 1 counteracts ISG15 antiviral activity by sequestering ISGylated viral proteins." in: Nature communications, Vol. 7, pp. 12754, (2018) (PubMed).

    Pietschmann, Buchwald, Müller, Knauer, Kögl, Heinzel, Krämer: "Differential regulation of PML-RAR? stability by the ubiquitin ligases SIAH1/SIAH2 and TRIAD1." in: The international journal of biochemistry & cell biology, Vol. 44, Issue 1, pp. 132-8, (2011) (PubMed).

    Krämer, Müller, Buchwald, Reichardt, Heinzel: "Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARalpha." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 22, Issue 5, pp. 1369-79, (2008) (PubMed).

  • 抗原
    UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
    别名
    UBE2L6 (UBE2L6 产品)
    别名
    UBE2L6 antibody, RIG-B antibody, UBCH8 antibody, 2810489I21Rik antibody, Ubce8 antibody, Ubcm8 antibody, UbcM8 antibody, ubiquitin conjugating enzyme E2 L6 antibody, ubiquitin-conjugating enzyme E2L 6 antibody, UBE2L6 antibody, Ube2l6 antibody
    背景
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.
    分子量
    17769
    基因ID
    9246
    NCBI登录号
    NP_004214, NP_937826
    UniProt
    O14933
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