我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

SNAIL 抗体 (N-Term)

Name: SNAIL 抗体 (N-Term)
SKU: ABIN388809
Availability: OutOfStock

SNAI1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01400 unconjugated

HepG2 cells were incubated with HGF for the time periods indicated. (SNAIL 抗体 (N-Term))

Formalin-fixed and paraffin-embedded human Spleen tissue reacted with SNAI1 antibody (N-term D24) (ABIN388809 and ABIN2850429) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (SNAIL 抗体 (N-Term))

IHC (p)

Western blot analysis of SNAI1 (arrow) using rabbit polyclonal hSNAI1-D24 (ABIN388809 and ABIN2850429). (SNAIL 抗体 (N-Term))

3 images

(26 references)

产品编号 ABIN388809

发货至: 中国

Datasheet as PDF

抗原 See all SNAIL (SNAI1) 抗体

SNAIL (SNAI1)
抗原表位
20

13

11

10

7

4

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 9-39, N-Term
适用
88

33

20

6

3

3

3

1
人
宿主
78

10

3

2
兔
Compatible Secondaries
克隆类型
83

10
多克隆
标记
59

6

4

4

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This SNAIL antibody is un-conjugated
应用范围
60

40

31

19

14

13

5

5

3

3

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This SNAI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-39 amino acids from the N-terminal region of human SNAI1.

克隆位点

RB01400

亚型

Ig Fraction

Top Product

Discover our top product SNAI1 Primary Antibody
anti-SNAIL (SNAI1) (C-Term) antibody
SNAI1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-SNAIL (SNAI1) (AA 1-100) antibody
SNAI1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-SNAIL (SNAI1) (C-Term) antibody
SNAI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-SNAIL (SNAI1) (N-Term) antibody
SNAI1 适用: 人, 小鼠, 大鼠, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-SNAIL (SNAI1) (AA 121-230) antibody
SNAI1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2G11 unconjugated

anti-SNAIL (SNAI1) (AA 1-264) antibody
SNAI1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-SNAIL (SNAI1) antibody
SNAI1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-SNAIL (SNAI1) antibody
SNAI1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-SNAIL (SNAI1) (pSer246) antibody
SNAI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-SNAIL (SNAI1) antibody
SNAI1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze-thaw cycles.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

有效期

6 months
Chiu, Wen, Wang, Hsu, Tsai, Hung, Tseng, Shyr: "Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers." in: Journal of translational medicine, Vol. 15, Issue 1, pp. 97, (2018) (PubMed).

Gil, Ciołczyk-Wierzbicka, Dulińska-Litewka, Laidler: "Integrin-linked kinase regulates cadherin switch in bladder cancer." in: Tumour biology, Vol. 37, Issue 11, pp. 15185-15191, (2017) (PubMed).

Ishikawa, Sreekumar, Spee, Nazari, Zhu, Kannan, Hinton: "αB-Crystallin Regulates Subretinal Fibrosis by Modulation of Epithelial-Mesenchymal Transition." in: The American journal of pathology, Vol. 186, Issue 4, pp. 859-73, (2016) (PubMed).

Nakamura, Nishikawa, Saito, Sakai, Sasaki, Hashimoto, Okamoto, Suehiro, Yamasaki, Sakaida: "Decitabine inhibits tumor cell proliferation and up-regulates e-cadherin expression in Epstein-Barr virus-associated gastric cancer." in: Journal of medical virology, (2016) (PubMed).

Wei, Zhang, Wang, Li, Wang, Sun, Shen, Yang, Zhou, Du: "FOXM1 promotes lung adenocarcinoma invasion and metastasis by upregulating SNAIL." in: International journal of biological sciences, Vol. 11, Issue 2, pp. 186-98, (2015) (PubMed).

Lee, Jeon, Ju, Jeong, Kim, Yoo, Park, Han, Kang: "Dlx-2 is implicated in TGF-?- and Wnt-induced epithelial-mesenchymal, glycolytic switch, and mitochondrial repression by Snail activation." in: International journal of oncology, Vol. 46, Issue 4, pp. 1768-80, (2015) (PubMed).

Fukui, Ogawa, Shimmura, Hatou, Ichihashi, Yaguchi, Hirayama, Kawakita, Tsubota: "Possible involvement of epithelial-mesenchymal transition in fibrosis associated with IgG4-related Mikulicz's disease." in: Modern rheumatology / the Japan Rheumatism Association, pp. 1-7, (2015) (PubMed).

Borges, Perez, Thompson, Radisky, Geiger, Storz: "Effective Targeting of Estrogen Receptor-Negative Breast Cancers with the Protein Kinase D Inhibitor CRT0066101." in: Molecular cancer therapeutics, Vol. 14, Issue 6, pp. 1306-16, (2015) (PubMed).

Liang, Wang, Zhu, Yang, An, Li, Niu, Chen, Tian: "BMP-7 attenuated silica-induced pulmonary fibrosis through modulation of the balance between TGF-?/Smad and BMP-7/Smad signaling pathway." in: Chemico-biological interactions, (2015) (PubMed).

Li, Jia, Ren, Liu, Gong, Wang, Zhang, Zhao: "Axl mediates tumor invasion and chemosensitivity through PI3K/Akt signaling pathway and is transcriptionally regulated by slug in breast carcinoma." in: IUBMB life, Vol. 66, Issue 7, pp. 507-18, (2014) (PubMed).

Chen, Miyazaki, Nishizawa, Kurahashi, Leach, Wang: "MTA3 regulates CGB5 and Snail genes in trophoblast." in: Biochemical and biophysical research communications, Vol. 433, Issue 4, pp. 379-84, (2013) (PubMed).

Sehrawat, Kim, Vogt, Singh: "Suppression of FOXQ1 in benzyl isothiocyanate-mediated inhibition of epithelial-mesenchymal transition in human breast cancer cells." in: Carcinogenesis, Vol. 34, Issue 4, pp. 864-73, (2013) (PubMed).

Muenst, Däster, Obermann, Droeser, Weber, von Holzen, Gao, Viehl, Oertli, Soysal: "Nuclear expression of snail is an independent negative prognostic factor in human breast cancer." in: Disease markers, Vol. 35, Issue 5, pp. 337-44, (2013) (PubMed).

Giner, Machado, Noguera, Villamon, Pellin, Calabuig-Fariñas, Peydro-Olaya, Navarro, Llombart-Bosch: "The epithelial mesenchymal transition process in wilms tumor: a study based on a xenograft model." in: Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry, Vol. 19, Issue 4, pp. 369-75, (2011) (PubMed).

Cheng, Auersperg, Leung: "Inhibition of p53 induces invasion of serous borderline ovarian tumor cells by accentuating PI3K/Akt-mediated suppression of E-cadherin." in: Oncogene, Vol. 30, Issue 9, pp. 1020-31, (2011) (PubMed).

Pham, Chen, Li, King, Angst, Dawson, Park, Reber, Hines, Eibl: "Loss of 15-hydroxyprostaglandin dehydrogenase increases prostaglandin E2 in pancreatic tumors." in: Pancreas, Vol. 39, Issue 3, pp. 332-9, (2010) (PubMed).

Matsuura, Chiang, Lai, He, Wang, Ramkumar, Uchida, Ryo, Lu, Liu: "Pin1 promotes transforming growth factor-beta-induced migration and invasion." in: The Journal of biological chemistry, Vol. 285, Issue 3, pp. 1754-64, (2010) (PubMed).

Arimoto-Ishida, Sakata, Sawada, Nakayama, Nishimoto, Mabuchi, Takeda, Yamamoto, Isobe, Okamoto, Lengyel, Suehara, Morishige, Kimura: "Up-regulation of alpha5-integrin by E-cadherin loss in hypoxia and its key role in the migration of extravillous trophoblast cells during early implantation." in: Endocrinology, Vol. 150, Issue 9, pp. 4306-15, (2009) (PubMed).

Ogawa, Shimmura, Kawakita, Yoshida, Kawakami, Tsubota: "Epithelial mesenchymal transition in human ocular chronic graft-versus-host disease." in: The American journal of pathology, Vol. 175, Issue 6, pp. 2372-81, (2009) (PubMed).

Kim, Choi, Choi, Cheong, Kim, Kwon, Kim, Choi: "Anti-invasive activity of histone deacetylase inhibitors via the induction of Egr-1 and the modulation of tight junction-related proteins in human hepatocarcinoma cells." in: BMB reports, Vol. 42, Issue 10, pp. 655-60, (2009) (PubMed).

show more references
抗原

SNAIL (SNAI1)

别名

SNAI1 (SNAI1 产品)

别名

SLUGH2 antibody, SNA antibody, SNAH antibody, SNAIL antibody, SNAIL1 antibody, dJ710H13.1 antibody, AI194338 antibody, Sna antibody, Sna1 antibody, Snail antibody, Snail1 antibody, SNAI1 antibody, BG:DS01845.1 antibody, CG3956 antibody, Dmel\\CG3956 antibody, Sco antibody, br28 antibody, br29 antibody, l(2)35Db antibody, l(2)br28 antibody, l(2)br29 antibody, l(3)br28 antibody, l35Db antibody, sn antibody, Xsnail antibody, sna antibody, snail1 antibody, xSna antibody, Snai antibody, sna2 antibody, snail2 antibody, cb643 antibody, sna-1 antibody, sna1 antibody, snai1 antibody, snail1a antibody, zgc:109820 antibody, snail family transcriptional repressor 1 antibody, snail family zinc finger 1 antibody, snail homolog 1 (Drosophila) antibody, snail antibody, zinc-finger transcription factor Snail antibody, snail family zinc finger 1 S homeolog antibody, protein escargot antibody, transcription factor protein antibody, snail zinc finger protein antibody, snail family zinc finger 1b antibody, snail family zinc finger 1a antibody, SNAI1 antibody, Snai1 antibody, sna antibody, snail antibody, snai1.S antibody, LOC410464 antibody, snai1b antibody, snai1a antibody

背景

The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo.

分子量

29083

NCBI登录号

NP_005976

UniProt

O95863

途径

Negative Regulation of intrinsic apoptotic Signaling