(5 references)-
- 抗原 See all SLUG products
- SLUG
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抗原表位
- AA 1-30, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLUG antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- B, M, Rat
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This SLUG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SLUG.
- 克隆位点
- RB15389
- 亚型
- Ig Fraction
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anti-SLUG (AA 98-129) antibody
适用: 人, 大鼠, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB01398 unconjugated
anti-SLUG (AA 5-120) antibody适用: 人, 大鼠, 兔 WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-SLUG antibody适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SLUG (Middle Region 2) antibody适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C.
- 有效期
- 6 months
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-
: "miR-33a suppresses the nuclear translocation of ?-catenin to enhance gemcitabine sensitivity in human pancreatic cancer cells." in: Tumour biology, (2015) (PubMed).
: "Androgen receptor inhibits epithelial-mesenchymal transition, migration, and invasion of PC-3 prostate cancer cells." in: Cancer letters, Vol. 369, Issue 1, pp. 103-11, (2015) (PubMed).
: "Hepatocyte growth factor activates Wnt pathway by transcriptional activation of LEF1 to facilitate tumor invasion." in: Carcinogenesis, Vol. 33, Issue 6, pp. 1142-8, (2012) (PubMed).
: "The postnatal accumulation of junctional E-cadherin is inversely correlated with the capacity for supporting cells to convert directly into sensory hair cells in mammalian balance organs." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 33, pp. 11855-66, (2011) (PubMed).
: "Ubiquitin ligase cullin 7 induces epithelial-mesenchymal transition in human choriocarcinoma cells." in: The Journal of biological chemistry, Vol. 285, Issue 14, pp. 10870-9, (2010) (PubMed).
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: "miR-33a suppresses the nuclear translocation of ?-catenin to enhance gemcitabine sensitivity in human pancreatic cancer cells." in: Tumour biology, (2015) (PubMed).
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- 抗原
- SLUG
- Abstract
- SLUG 产品
- 别名
- Slug antibody, Slugh antibody, Snail2 antibody, SLUG antibody, SLUGH antibody, SLUGH1 antibody, SNAIL2 antibody, WS2D antibody, snail family zinc finger 2 antibody, snail family transcriptional repressor 2 antibody, Snai2 antibody, SNAI2 antibody
- 背景
- SLUG is a member of the Snail family of C2H2-type zinc finger transcription factors. This protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in the gene encoding SLUG may be associated with sporadic cases of neural tube defects.
- 分子量
- 29986
- NCBI登录号
- NP_003059
- UniProt
- O43623
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