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SOX2 抗体 (N-Term)

Name: SOX2 抗体 (N-Term)
SKU: ABIN388797
Availability: OutOfStock

SOX2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB14026 unconjugated

Western blot analysis of SOX2 Antibody (N-term) in 293 cell line lysates (35 μg/lane). (SOX2 抗体 (N-Term))

Flow cytometric analysis of NCI- cells using SOX2 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). (SOX2 抗体 (N-Term))

FACS

Immunofluorescence analysis of SOX2 Antibody (N-term) (ABIN388797 and ABIN2839124) in HeLa cells. (SOX2 抗体 (N-Term))

Western blot analysis of SOX2 (arrow) using rabbit polyclonal SOX2 Antibody (N-term) (ABIN388797 and ABIN2839124). (SOX2 抗体 (N-Term))

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with SOX2 antibody (N-term) (ABIN388797 and ABIN2839124) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (SOX2 抗体 (N-Term))

IHC (p)

5 images

(2 references)

产品编号 ABIN388797

发货至: 中国

Datasheet as PDF

抗原 See all SOX2 抗体

SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
抗原表位
18

16

16

15

15

14

13

11

10

10

9

8

7

4

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 89-119, N-Term
适用
201

95

69

21

13

10

10

10

8

8

7

7

5

5

2

2

1

1

1
人
宿主
164

42

2
兔
Compatible Secondaries
克隆类型
163

45
多克隆
标记
102

16

15

10

10

9

3

3

3

3

3

3

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1
This SOX2 antibody is un-conjugated
应用范围
162

110

46

45

43

40

40

28

25

22

17

16

12

6

4

4

4

3

2

1

1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

Zf, X, C, M, Sh

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This SOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-119 amino acids from the N-terminal region of human SOX2.

克隆位点

RB14026

亚型

Ig Fraction

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anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 227-317) antibody
SOX2 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-140) antibody
SOX2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-317) antibody
SOX2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 176-305) antibody
SOX2 适用: 人, 小鼠 WB, ELISA, IHC, Coat, StM 宿主: 小鼠 Monoclonal SOX2-1791 unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (N-Term) antibody
SOX2 适用: 人, 小鼠, 大鼠, 山羊, Pig, Cow, 绵羊, 斑马鱼, 马, 兔, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody
SOX2 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 10F10 unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (Middle Region) antibody
SOX2 适用: 人, 小鼠, 大鼠, 山羊, Cow, 绵羊, 斑马鱼, 马, 兔, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 89-119) antibody
SOX2 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 251-284) antibody
SOX2 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB14259 unconjugated

应用备注

IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Schouten, Fratantoni, Hubens, Piersma, Pham, Bielefeld, Voskuyl, Lucassen, Jimenez, Fitzsimons: "MicroRNA-124 and -137 cooperativity controls caspase-3 activity through BCL2L13 in hippocampal neural stem cells." in: Scientific reports, Vol. 5, pp. 12448, (2015) (PubMed).

Su, Qi: "Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation." in: Human molecular genetics, Vol. 22, Issue 22, pp. 4545-61, (2013) (PubMed).
抗原

SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

别名

SOX2 (SOX2 产品)

别名

ANOP3 antibody, MCOPS3 antibody, RGD1565646 antibody, Sox-2 antibody, lcc antibody, ysb antibody, cb236 antibody, wu:fb83g04 antibody, wu:fc14d07 antibody, zgc:65860 antibody, zgc:77389 antibody, SRY-box2 antibody, Xsox-2 antibody, anop3 antibody, mcops3 antibody, sox-2 antibody, SRY-box 2 antibody, SRY box 2 antibody, SRY (sex determining region Y)-box 2 antibody, SRY-box 2 S homeolog antibody, SOX2 antibody, Sox2 antibody, sox2 antibody, sox2.S antibody

背景

The intronless gene for SOX2 encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.

分子量

34310

基因ID

6657

NCBI登录号

NP_003097

UniProt

P48431

途径

Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis