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PDX1 抗体 (AA 1-30)
PDX1
适用: 人
WB, IF, IHC (p)
宿主: 兔
Polyclonal
RB15204
unconjugated
PDX1抗体详情
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抗原
See all PDX1 抗体
PDX1
(Pancreatic and Duodenal Homeobox 1 (PDX1))
抗原表位
All epitopes for PDX1 抗体
AA 1-30
适用
All reactivities for PDX1 抗体
人
宿主
All hosts for PDX1 抗体
兔
克隆类型
All clonalities for PDX1 抗体
多克隆
标记
All conjugates for PDX1 抗体
This PDX1 antibody is un-conjugated
应用范围
All applications for PDX1 抗体
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
预测反应
M, Rat
纯化方法
This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This PDX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human PDX1.
克隆位点
RB15204
亚型
Ig Fraction
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Alternatives
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使用细节
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应用备注
IF: 1:100. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期
6 months
PDX1目标详情
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抗原
PDX1
(Pancreatic and Duodenal Homeobox 1 (PDX1))
别名
PDX1 (PDX1 产品 )
别名
GSF antibody, IDX-1 antibody, IPF1 antibody, IUF1 antibody, MODY4 antibody, PDX-1 antibody, STF-1 antibody, ipf1 antibody, PDX1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, pdx-1 antibody, Idx1 antibody, Stf1 antibody, zgc:100874 antibody, XlHbox-8 antibody, xlhbox8 antibody, pancreatic and duodenal homeobox 1 antibody, pancreatic and duodenal homeobox 1 S homeolog antibody, PDX1 antibody, pdx1 antibody, Pdx1 antibody, pdx1.S antibody
背景
PDX1, located in the mitochondrial matrix, is required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. Eukaryotic pyruvate dehydrogenase complexes are organized about a core consisting of the oligomeric dihydrolipoamide acetyl-transferase, around which are arranged multiple copies of pyruvate dehydrogenase, dihydrolipoamide dehydrogenase and protein X bound by noncovalent bonds. Defects in PDHX are a cause of lacticacidemia. PDX1 belongs to the 2-oxoacid dehydrogenase family and contains 1 lipoyl-binding domain.
分子量
54122
基因ID
8050
NCBI登录号
NP_001128496 , NP_001159630 , NP_003468
UniProt
O00330
途径
Nuclear Receptor Transcription Pathway , Positive Regulation of Peptide Hormone Secretion , Steroid Hormone Mediated Signaling Pathway , Hormone Transport , Carbohydrate Homeostasis , Chromatin Binding , Maintenance of Protein Location
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