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PDX1 抗体 (C-Term)

PDX1 适用: 人 WB 宿主: 兔 Polyclonal RB02861-02862 unconjugated
产品编号 ABIN388773
发货至: 中国
  • 抗原 See all PDX1 抗体
    PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
    抗原表位
    • 21
    • 15
    • 15
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 429-459, C-Term
    适用
    • 114
    • 45
    • 34
    • 15
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 127
    • 8
    • 2
    克隆类型
    • 122
    • 15
    多克隆
    标记
    • 61
    • 12
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDX1 antibody is un-conjugated
    应用范围
    • 84
    • 63
    • 32
    • 20
    • 17
    • 14
    • 14
    • 12
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This PDX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 429-459 amino acids from the C-terminal region of human PDX1.
    克隆位点
    RB02861-02862
    亚型
    Ig Fraction
    Top Product
    Discover our top product PDX1 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
    别名
    PDX1 (PDX1 产品)
    别名
    GSF antibody, IDX-1 antibody, IPF1 antibody, IUF1 antibody, MODY4 antibody, PDX-1 antibody, STF-1 antibody, ipf1 antibody, PDX1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, pdx-1 antibody, Idx1 antibody, Stf1 antibody, zgc:100874 antibody, XlHbox-8 antibody, xlhbox8 antibody, pancreatic and duodenal homeobox 1 antibody, pancreatic and duodenal homeobox 1 S homeolog antibody, PDX1 antibody, pdx1 antibody, Pdx1 antibody, pdx1.S antibody
    背景
    PDX1, located in the mitochondrial matrix, is required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. Eukaryotic pyruvate dehydrogenase complexes are organized about a core consisting of the oligomeric dihydrolipoamide acetyl-transferase, around which are arranged multiple copies of pyruvate dehydrogenase, dihydrolipoamide dehydrogenase and protein X bound by noncovalent bonds. Defects in PDHX are a cause of lacticacidemia. PDX1 belongs to the 2-oxoacid dehydrogenase family and contains 1 lipoyl-binding domain.
    分子量
    54122
    基因ID
    8050
    NCBI登录号
    NP_001128496, NP_001159630, NP_003468
    UniProt
    O00330
    途径
    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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