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BMPR2 抗体 (N-Term)

BMPR2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB01778 unconjugated
产品编号 ABIN388741
发货至: 中国
  • 抗原 See all BMPR2 抗体
    BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
    抗原表位
    • 15
    • 9
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-59, N-Term
    适用
    • 59
    • 42
    • 16
    • 3
    • 1
    宿主
    • 53
    • 6
    • 1
    克隆类型
    • 54
    • 6
    多克隆
    标记
    • 32
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BMPR2 antibody is un-conjugated
    应用范围
    • 47
    • 26
    • 18
    • 13
    • 13
    • 13
    • 9
    • 8
    • 8
    • 4
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This BMPR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-59 amino acids from the N-terminal region of human BMPR2.
    克隆位点
    RB01778
    亚型
    Ig Fraction
    Top Product
    Discover our top product BMPR2 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze-thaw cycles.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    有效期
    6 months
  • Lynch, Ahsan: "Correlating the Effects of Bone Morphogenic Protein to Secreted Soluble Factors from Fibroblasts and Mesenchymal Stem Cells in Regulating Regenerative Processes In Vitro." in: Tissue engineering. Part A, (2014) (PubMed).

    Srikanth, Kim, Das, Kessler: "BMP signaling induces astrocytic differentiation of clinically derived oligodendroglioma propagating cells." in: Molecular cancer research : MCR, Vol. 12, Issue 2, pp. 283-94, (2014) (PubMed).

    Li, Cao, Ma, Wang, Zhang, Luo, Chen, Wu, Meng, Zhang, Yuan, Ma, Huang: "Roles of miR-1-1 and miR-181c in ventricular septal defects." in: International journal of cardiology, Vol. 168, Issue 2, pp. 1441-6, (2013) (PubMed).

    Zhang, Mu, Zhou, Vrijens, Roussel, Jiang, Yan: "Binding of carbon nanotube to BMP receptor 2 enhances cell differentiation and inhibits apoptosis via regulating bHLH transcription factors." in: Cell death & disease, Vol. 3, pp. e308, (2012) (PubMed).

    Jara, Chacón, Burgos, Droguett, Valdivieso, Ortiz, Troncoso, Mezzano: "Expression of gremlin, a bone morphogenetic protein antagonist,is associated with vascular calcification in uraemia." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 24, Issue 4, pp. 1121-9, (2009) (PubMed).

    Sehgal, Mukhopadhyay, Xu, Patel, Shah: "Dysfunction of Golgi tethers, SNAREs, and SNAPs in monocrotaline-induced pulmonary hypertension." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 292, Issue 6, pp. L1526-42, (2007) (PubMed).

    Ramos, Lamé, Segall, Wilson: "The BMP type II receptor is located in lipid rafts, including caveolae, of pulmonary endothelium in vivo and in vitro." in: Vascular pharmacology, Vol. 44, Issue 1, pp. 50-9, (2005) (PubMed).

  • 抗原
    BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
    别名
    BMPR2 (BMPR2 产品)
    别名
    BMPR-II antibody, BMPR3 antibody, BMR2 antibody, BRK-3 antibody, PPH1 antibody, T-ALK antibody, 2610024H22Rik antibody, AL117858 antibody, AW546137 antibody, BB189135 antibody, BMP-2 antibody, BMPR-2 antibody, BMPRII antibody, Gm20272 antibody, Bmpr-II antibody, bmprii antibody, bone morphogenetic protein receptor type 2 antibody, bone morphogenetic protein receptor, type II b (serine/threonine kinase) antibody, bone morphogenetic protein receptor, type II (serine/threonine kinase) antibody, BMPR2 antibody, bmpr2b antibody, Bmpr2 antibody
    背景
    BMPR2 is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in BMPR2 have been associated with primary pulmonary hypertension.
    分子量
    115201
    基因ID
    659
    NCBI登录号
    NP_001195
    UniProt
    Q13873
    途径
    Growth Factor Binding
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