UVRAG 抗体 (C-Term)
(7 references)-
- 抗原 See all UVRAG 抗体
- UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
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抗原表位
- AA 666-699, C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UVRAG antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This UVRAG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 666-699 amino acids from the C-terminal region of human UVRAG.
- 克隆位点
- RB10849
- 亚型
- Ig Fraction
- Top Product
- Discover our top product UVRAG Primary Antibody
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anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 501-699) antibody
UVRAG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 375-425) antibodyUVRAG 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 601-699) antibodyUVRAG 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E8 unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) antibodyUVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (HRP)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal HRP
anti-UV Radiation Resistance Associated Gene (UVRAG) (C-Term) antibody (FITC)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal FITC
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (Biotin)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-UV Radiation Resistance Associated Gene (UVRAG) (C-Term) antibody (PE)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PE
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (PE)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PE
anti-UV Radiation Resistance Associated Gene (UVRAG) (C-Term) antibody (PerCP)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PerCP
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- 应用备注
- IF: 1:10~50. IF: 1:200. WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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: "Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, (2011) (PubMed).
: "The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression." in: The Journal of biological chemistry, Vol. 286, Issue 1, pp. 185-91, (2011) (PubMed).
: "Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a ?-secretase-independent manner." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 8, pp. 2781-91, (2011) (PubMed).
: "Rubicon controls endosome maturation as a Rab7 effector." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 45, pp. 19338-43, (2010) (PubMed).
: "Biochemical isolation and characterization of the tubulovesicular LC3-positive autophagosomal compartment." in: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 1371-83, (2010) (PubMed).
: "Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 49, pp. 19211-6, (2008) (PubMed).
: "Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells." in: The Journal of biological chemistry, Vol. 283, Issue 28, pp. 19665-77, (2008) (PubMed).
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: "Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, (2011) (PubMed).
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- 抗原
- UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
- 别名
- UVRAG (UVRAG 产品)
- 别名
- DHTX antibody, VPS38 antibody, p63 antibody, 9530039D02Rik antibody, AI648770 antibody, BB124205 antibody, Uvrag1 antibody, Uvragl antibody, zgc:56164 antibody, uvrag antibody, MGC81810 antibody, UVRAG antibody, MGC131135 antibody, CG6116 antibody, Dmel\\CG6116 antibody, UV radiation resistance associated antibody, UV radiation resistance associated gene antibody, UV radiation resistance associated S homeolog antibody, UV radiation resistance associated L homeolog antibody, UV-resistance associated gene antibody, UVRAG antibody, Uvrag antibody, uvrag antibody, uvrag.S antibody, uvrag.L antibody
- 背景
- UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.
- 分子量
- 78151
- 基因ID
- 7405
- NCBI登录号
- NP_003360
- UniProt
- Q9P2Y5
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