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GABARAP 抗体 (AA 1-30)

Name: GABARAP 抗体 (AA 1-30)
SKU: ABIN388564
Availability: OutOfStock

GABARAP 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB11846 unconjugated

All lanes : Anti-Autophagy GABAR Antibody (N-term) at 1:1000-1 :2000 dilution Lane 1: human fetal kidney lysate Lane 2: SH-SY5Y whole cell lysate Lane 3: mouse brain lysate Lane 4: rat brain whole cell lysate Lane 5: HepG2 whole cell lysate Lane 6: human fetal brain lysate Lane 7: C2C12 whole cell lysate Lysates/proteins at 20 μg per lane. (GABARAP 抗体 (AA 1-30))

IHC (p)

Immunofluorescent analysis of 4 % paraformaldehyde-fixed, 0. (GABARAP 抗体 (AA 1-30))

IHC (p)

5 images

(4 references)

产品编号 ABIN388564

发货至: 中国

Datasheet as PDF

抗原 See all GABARAP 抗体

GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))
抗原表位
24

15

8

6

6

5

4

2

2

1

1

1

1

1
AA 1-30
适用
92

28

27

7

6

6

6

6

3

3

3

2

1

1

1
人, 小鼠, 大鼠
宿主
87

10

1
兔
Compatible Secondaries
克隆类型
81

17
多克隆
标记
35

10

9

7

5

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This GABARAP antibody is un-conjugated
应用范围
64

35

31

19

18

13

13

6

3

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

B, Rb

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This GABARAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids of human GABARAP.

克隆位点

RB11846

亚型

IgG

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GABARAP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-GABA(A) Receptor-Associated Protein (GABARAP) (AA 1-30) antibody
GABARAP 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated

anti-GABA(A) Receptor-Associated Protein (GABARAP) (AA 1-31), (N-Term) antibody
GABARAP 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-GABA(A) Receptor-Associated Protein (GABARAP) (AA 1-117) antibody
GABARAP 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated

anti-GABA(A) Receptor-Associated Protein (GABARAP) (N-Term) antibody
GABARAP 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-GABA(A) Receptor-Associated Protein (GABARAP) (N-Term) antibody (HRP)
GABARAP 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal HRP

anti-GABA(A) Receptor-Associated Protein (GABARAP) (N-Term) antibody (FITC)
GABARAP 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal FITC

anti-GABA(A) Receptor-Associated Protein (GABARAP) (C-Term) antibody (FITC)
GABARAP 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal FITC

anti-GABA(A) Receptor-Associated Protein (GABARAP) (C-Term) antibody (Alkaline Phosphatase (AP))
GABARAP 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)

anti-GABA(A) Receptor-Associated Protein (GABARAP) (N-Term) antibody (Biotin)
GABARAP 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Biotin

应用备注

IF: 1:25. IF: 1:25. WB: 1:1000-1 :2000. IHC-P: 1:25. IHC-P: 1:25

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Joachim, Razi, Judith, Wirth, Calamita, Encheva, Dynlacht, Snijders, OReilly, Jefferies, Tooze: "Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy." in: Current biology : CB, Vol. 27, Issue 14, pp. 2123-2136.e7, (2018) (PubMed).

Clough, Wright, Pereira, Hirst, Johnston, Henriques, Frickel: "K63-Linked Ubiquitination Targets Toxoplasma gondii for Endo-lysosomal Destruction in IFNγ-Stimulated Human Cells." in: PLoS pathogens, Vol. 12, Issue 11, pp. e1006027, (2017) (PubMed).

Egan, Chun, Vamos, Zou, Rong, Miller, Lou, Raveendra-Panickar, Yang, Sheffler, Teriete, Asara, Turk, Cosford, Shaw: "Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates." in: Molecular cell, Vol. 59, Issue 2, pp. 285-97, (2015) (PubMed).

Orfali, ODonovan, Nyhan, Britschgi, Tschan, Cahill, Mongan, Gudas, McKenna: "Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation." in: Experimental hematology, Vol. 43, Issue 9, pp. 781-93.e2, (2015) (PubMed).
抗原

GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

别名

GABARAP (GABARAP 产品)

别名

GABARAP antibody, ATG8A antibody, GABARAP-a antibody, MM46 antibody, gabarap antibody, mg:bb02b03 antibody, GABA type A receptor-associated protein antibody, gamma-aminobutyric acid receptor-associated protein antibody, GABA(A) receptor-associated protein a antibody, gamma-aminobutyric acid receptor associated protein antibody, GABARAP antibody, LOC5568843 antibody, Gabarap antibody, gabarapa antibody

背景

Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. GABARAP is GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton.

分子量

13918

基因ID

11337

NCBI登录号

NP_009209

UniProt

O95166

途径

Autophagy