Beclin 1 抗体 (AA 181-210)
(5 references)-
- 抗原 See all Beclin 1 (BECN1) 抗体
- Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
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抗原表位
- AA 181-210
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Beclin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- B, C
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This Beclin 1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-210 amino acids from human Beclin 1.
- 克隆位点
- RB7461
- 亚型
- Ig Fraction
- Top Product
- Discover our top product BECN1 Primary Antibody
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anti-Beclin 1, Autophagy Related (BECN1) (AA 201-330) antibody
BECN1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人, 大鼠, 犬 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1F1 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人, 大鼠, 猴 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人, 大鼠, 猴, 犬 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 3C3 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2A4 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 1-354) antibodyBECN1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 210-239) antibodyBECN1 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB7463 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 210-239) antibodyBECN1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (C-Term) antibodyBECN1 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 181-210) antibodyBECN1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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: "Curcumin induces apoptotic cell death and protective autophagy in human gastric cancer cells." in: Oncology reports, Vol. 37, Issue 6, pp. 3459-3466, (2018) (PubMed).
: "Expression of LC3 and Beclin 1 in the spinal dorsal horn following spinal nerve ligation-induced neuropathic pain." in: Brain research, Vol. 1519, pp. 31-9, (2013) (PubMed).
: "Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma." in: Science translational medicine, Vol. 5, Issue 202, pp. 202ra123, (2013) (PubMed).
: "Triterpenes from Ganoderma Lucidum induce autophagy in colon cancer through the inhibition of p38 mitogen-activated kinase (p38 MAPK)." in: Nutrition and cancer, Vol. 62, Issue 5, pp. 630-40, (2010) (PubMed).
: "Chondrocyte autophagy is stimulated by HIF-1 dependent AMPK activation and mTOR suppression." in: Pediatric nephrology (Berlin, Germany), Vol. 25, Issue 4, pp. 633-42, (2010) (PubMed).
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: "Curcumin induces apoptotic cell death and protective autophagy in human gastric cancer cells." in: Oncology reports, Vol. 37, Issue 6, pp. 3459-3466, (2018) (PubMed).
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- 抗原
- Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
- 别名
- Beclin 1 (BECN1 产品)
- 别名
- beclin-1 antibody, atg6 antibody, vps30 antibody, beclin1 antibody, Beclin-1 antibody, becn1 antibody, zgc:73097 antibody, ATG6 antibody, VPS30 antibody, 4921513J16Rik antibody, 5430417M23Rik antibody, Atg6 antibody, beclin 1 antibody, beclin 1, autophagy related antibody, beclin 1 protein antibody, beclin-1 antibody, beclin family protein antibody, beclin 1, autophagy related L homeolog antibody, BECN1 antibody, becn1 antibody, atg6 antibody, CpipJ_CPIJ011087 antibody, PTRG_07825 antibody, SJAG_01876 antibody, Becn1 antibody, becn1.L antibody
- 背景
- Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Beclin 1 plays a role in two fundamentally important cell biological pathways: autophagy and apoptosis. Beclin 1 is thought to function as a VPS and autophagy protein as part of a complex with Class III PI3 kinase, Vps34.
- 分子量
- 51896
- 基因ID
- 8678
- NCBI登录号
- NP_003757
- UniProt
- Q14457
- 途径
- Autophagy
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