我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

ATG7 抗体 (AA 494-523)

Name: ATG7 抗体 (AA 494-523)
SKU: ABIN388522
Availability: OutOfStock

ATG7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7472 unconjugated

All lanes : Anti-G7L Antibody at 1:1000 dilution Lane 1: Ba/F3 whole cell lysate Lane 2: Caki-1 whole cell lysate Lane 3: HepG2 whole cell lysate Lysates/proteins at 20 μg per lane. (ATG7 抗体 (AA 494-523))

IHC (p)

2 images

(10 references)

产品编号 ABIN388522

发货至: 中国

Datasheet as PDF

抗原 See all ATG7 抗体

ATG7 (ATG7 Autophagy Related 7 (ATG7))
抗原表位
17

16

15

9

6

6

6

6

5

4

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 494-523
适用
116

38

26

2

1

1

1

1

1

1

1
人, 小鼠
宿主
104

13

2
兔
Compatible Secondaries
克隆类型
100

19
多克隆
标记
58

9

8

7

6

5

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This ATG7 antibody is un-conjugated
应用范围
98

58

47

23

16

14

14

13

12

7

5

4

3

2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This ATG7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 494-523 amino acids from human ATG7.

克隆位点

RB7472

亚型

Ig Fraction

Top Product

Discover our top product ATG7 Primary Antibody
anti-ATG7 Autophagy Related 7 (ATG7) (AA 429-488) antibody
ATG7 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 500-676) antibody
ATG7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 477-698) antibody
ATG7 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 540-569), (C-Term) antibody
ATG7 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7474 unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 22-51) antibody
ATG7 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 494-523) antibody
ATG7 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (APC)
ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal APC

anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (Atto 594)
ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 594

anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (Atto 488)
ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 488

anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (Atto 390)
ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 390

应用备注

WB: 1:1000. IHC-P: 1:25

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Li, Zhou, Yang, Li, Zhang, Zheng: "Curcumin induces apoptotic cell death and protective autophagy in human gastric cancer cells." in: Oncology reports, Vol. 37, Issue 6, pp. 3459-3466, (2018) (PubMed).

Oikonomou, Moretti, Renga, Galosi, Borghi, Pariano, Puccetti, Palmerini, Amico, Carotti, Prezioso, Spolzino, Finocchi, Rossi, Velardi, Aversa, Napolioni, Romani: "Noncanonical Fungal Autophagy Inhibits Inflammation in Response to IFN-γ via DAPK1." in: Cell host & microbe, Vol. 20, Issue 6, pp. 744-757, (2017) (PubMed).

Gao, Li, Ding, Qi, Yang: "Cepharanthine Induces Autophagy, Apoptosis and Cell Cycle Arrest in Breast Cancer Cells." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 41, Issue 4, pp. 1633-1648, (2017) (PubMed).

Laggner, Pollreisz, Schmidinger, Schmidt-Erfurth, Chen: "Autophagy mediates cell cycle response by regulating nucleocytoplasmic transport of PAX6 in limbal stem cells under ultraviolet-A stress." in: PLoS ONE, Vol. 12, Issue 7, pp. e0180868, (2017) (PubMed).

Okamoto, Sakimoto, Imai, Senoo, Shidoji: "Induction of an incomplete autophagic response by cancer-preventive geranylgeranoic acid (GGA) in a human hepatoma-derived cell line." in: The Biochemical journal, Vol. 440, Issue 1, pp. 63-71, (2011) (PubMed).

Wei, Kulp, Chen: "Energy restriction as an antitumor target of thiazolidinediones." in: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 9780-91, (2010) (PubMed).

Yang, Liu, Goga, Kim, Yuneva, Bishop: "Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 31, pp. 13836-41, (2010) (PubMed).

Bigford, Alonso, Dietrich, Keane: "A novel protein complex in membrane rafts linking the NR2B glutamate receptor and autophagy is disrupted following traumatic brain injury." in: Journal of neurotrauma, Vol. 26, Issue 5, pp. 703-20, (2009) (PubMed).

Ding, Shi, Zhou, Qiu, Xu, Dai, Shi, Wang, Ke, Wu, Fan: "Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma." in: Cancer research, Vol. 68, Issue 22, pp. 9167-75, (2008) (PubMed).

Xu, Liang, Haridas, Gaikwad, Connolly, Mills, Gutterman: "A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase." in: Cell death and differentiation, Vol. 14, Issue 11, pp. 1948-57, (2007) (PubMed).
抗原

ATG7 (ATG7 Autophagy Related 7 (ATG7))

别名

ATG7 (ATG7 产品)

别名

APG7-LIKE antibody, APG7L antibody, GSA7 antibody, D8 antibody, UBA1B antibody, UBE1L antibody, UBE2 antibody, Ube1l antibody, 1300004C08Rik antibody, AO090001000744 antibody, atg7 antibody, 1810013K23Rik antibody, Agp7 antibody, Apg7l antibody, Atg7l antibody, ATAPG7 antibody, ATATG7 antibody, ATG7 antibody, AUTOPHAGY 7 antibody, AUTOPHAGY-RELATED 7 antibody, K15I22.10 antibody, K15I22_10 antibody, autophagy related 7 antibody, ubiquitin like modifier activating enzyme 7 antibody, ubiquitin-like modifier activating enzyme 7 antibody, autophagy-related protein 7 antibody, Autophagy-related protein 7 antibody, Apg7p antibody, ThiF family protein antibody, ubiquitin-like conjugating enzyme Atg7 antibody, ATG7 antibody, UBA7 antibody, Uba7 antibody, ANI_1_3368024 antibody, AOR_1_1338164 antibody, PTRG_02236 antibody, PAAG_00287 antibody, PITG_12537 antibody, atg7 antibody, Atg7 antibody, APG7 antibody

背景

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG7 functions as an E1 enzyme essential for multisubstrates such as GABARAPL1 and ATG12. APG3L is an E2-like conjugating enzyme facilitating covalent binding of APG8 (MAP1LC3) to phosphatidylethanolamine (PE). APG7 (an E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with APG3. Formation of the PE conjugate is essential for autophagy.

分子量

77960

基因ID

10533

NCBI登录号

NP_001129503, NP_001138384, NP_006386

UniProt

O95352

途径

Response to Water Deprivation, Autophagy