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ATG4B 抗体 (N-Term)

Name: ATG4B 抗体 (N-Term)
SKU: ABIN388494
Availability: OutOfStock

ATG4B 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7496 unconjugated

Western blot analysis of anti-hG4B-R31 Pab 1809a in 293 cell line lysates transiently transfected with the ATG4B gene (2 μg/lane). (ATG4B 抗体 (N-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (ATG4B 抗体 (N-Term))

IHC (p)

The anti-G4B Pab 1809a is used in Western blot to detect G4B in CEM tissue lysate (ATG4B 抗体 (N-Term))

G4B Antibody (R31) 1809a western blot analysis in mouse cerebellum tissue lysates (35 μg/lane). (ATG4B 抗体 (N-Term))

4 images

(2 references)

产品编号 ABIN388494

发货至: 中国

Datasheet as PDF

抗原 See all ATG4B 抗体

ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
抗原表位
21

16

15

13

12

8

8

7

7

7

6

5

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 16-45, N-Term
适用
116

49

26

8

7

6

6

5

5

4

3

3

3

2

1

1
人, 小鼠
宿主
114

4
兔
Compatible Secondaries
克隆类型
114

4
多克隆
标记
48

10

9

8

7

6

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This ATG4B antibody is un-conjugated
应用范围
92

40

26

21

19

16

13

13

11

3

3

2

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This ATG4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-45 amino acids from the N-terminal region of human ATG4B.

克隆位点

RB7496

亚型

Ig Fraction

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anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 1-221) antibody
ATG4B 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 6C3C5 unconjugated

anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 350-400) antibody
ATG4B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 358-390), (C-Term) antibody
ATG4B 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB7560 unconjugated

anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 85-200) antibody
ATG4B 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 23-53), (N-Term) antibody
ATG4B 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 94-106) antibody (HRP)
ATG4B 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal HRP

anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 62-73) antibody (FITC)
ATG4B 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal FITC

anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 94-106) antibody (FITC)
ATG4B 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal FITC

anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 62-73) antibody (Alkaline Phosphatase (AP))
ATG4B 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)

anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 94-106) antibody (Alkaline Phosphatase (AP))
ATG4B 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)

应用备注

WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Yang, Zhao, Mei, Jiang, Geng, Li, Yao, Liu, Kong, Cao: "HMGA2 plays an important role in Cr (VI)-induced autophagy." in: International journal of cancer, Vol. 141, Issue 5, pp. 986-997, (2017) (PubMed).

Garneau, Alvarez, Paquin, Lussier, Rancourt, Tremblay, Beaulieu, Rivard: "Nuclear expression of E2F4 induces cell death via multiple pathways in normal human intestinal epithelial crypt cells but not in colon cancer cells." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 293, Issue 4, pp. G758-72, (2007) (PubMed).
抗原

ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

别名

ATG4B (ATG4B 产品)

别名

apg4b antibody, APG4B antibody, AUTL1 antibody, 2510009N07Rik antibody, AW048066 antibody, Apg4b antibody, Atg4bl antibody, Autl1 antibody, Aut2b2 antibody, autophagy related 4B cysteine peptidase antibody, autophagy-related 4b antibody, Peptidase family C54 protein antibody, cysteine protease ATG4B antibody, ATG4 autophagy related 4 homolog B (S. cerevisiae) antibody, autophagy related 4B, cysteine peptidase antibody, autophagy related 4B, cysteine peptidase L homeolog antibody, ATG4B antibody, Atg4b antibody, AT3G59950 antibody, Tsp_08582 antibody, Tsp_11599 antibody, atg4b antibody, atg4b.L antibody

背景

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4 is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.

分子量

44294

基因ID

23192

NCBI登录号

NP_037457, NP_847896

UniProt

Q9Y4P1

途径

Autophagy