Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
纯化方法
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
免疫原
This Bmp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 957-986 amino acids from the C-terminal region of human Bmp1.
OI13 antibody, PCOLC antibody, PCP antibody, PCP2 antibody, TLD antibody, Pcp antibody, Tld antibody, BMP1 antibody, submp antibody, tld antibody, xtld antibody, bmp-1 antibody, pcolc antibody, xbmp1 antibody, tolloid antibody, BMP-1 antibody, bmp1 antibody, bmp1a antibody, bone morphogenetic protein 1 antibody, Bone morphogenetic protein 1 antibody, bone morphogenetic protein 1 S homeolog antibody, bone morphogenetic protein 1, like antibody, BMP1 antibody, Bmp1 antibody, bmp1 antibody, bmp1.S antibody, bmp1l antibody
背景
The BMP1 locus encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, BMP1 encodes a protein that is not closely related to other known growth factors. BMP1 protein and procollagen C proteinase (PCP), a secreted metalloprotease requiring calcium and needed for cartilage and bone formation, are identical. PCP or BMP1 protein cleaves the C-terminal propeptides of procollagen I, II, and III and its activity is increased by the procollagen C-endopeptidase enhancer protein. The BMP1 gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.