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TXN 抗体 (N-Term)

TXN 适用: 人 WB 宿主: 兔 Polyclonal RB5217 unconjugated
产品编号 ABIN388136
发货至: 中国
  • 抗原 See all TXN 抗体
    TXN (Thioredoxin (TXN))
    抗原表位
    • 20
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    适用
    • 70
    • 28
    • 27
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 75
    • 16
    克隆类型
    • 66
    • 25
    多克隆
    标记
    • 41
    • 17
    • 12
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This TXN antibody is un-conjugated
    应用范围
    • 64
    • 35
    • 29
    • 12
    • 12
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This Thioredoxin (TRX) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Thioredoxin (TRX).
    克隆位点
    RB5217
    亚型
    Ig Fraction
    Top Product
    Discover our top product TXN Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    TXN (Thioredoxin (TXN))
    别名
    Thioredoxin (TRX) (TXN 产品)
    别名
    TRDX antibody, TRX antibody, TRX1 antibody, ADF antibody, AW550880 antibody, Trx1 antibody, Txn antibody, trx antibody, TXN antibody, SCM1.18 antibody, trxA3 antibody, thioredoxin antibody, TR-1 antibody, Trx-1 antibody, thioredoxin antibody, thioredoxin 1 antibody, thioredoxin L homeolog antibody, similar to 44RRORF109c hypothetical protein; similar to bacterial thioredoxin (SwissProt P06544) antibody, thioredoxin pseudogene antibody, cytosolic thioredoxin Trx1 antibody, TXN antibody, Txn1 antibody, txn.L antibody, txn antibody, trx antibody, SCO0885 antibody, PHG25ORF099c antibody, LOC100349046 antibody, Txn antibody, trx1 antibody
    背景
    Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1.Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.
    分子量
    11737
    基因ID
    7295
    NCBI登录号
    NP_001231867, NP_003320
    UniProt
    P10599
    途径
    Carbohydrate Homeostasis, Cell RedoxHomeostasis
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