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GRP78 抗体

Name: GRP78 抗体
SKU: ABIN388133
Availability: OutOfStock

HSPA5 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB1768 unconjugated

The anti-HS Pab (ABIN388133 and ABIN2846370) is used in Western blot to detect HS in mouse liver tissue lysate. (GRP78 抗体)

HS Antibody (ABIN388133 and ABIN2846370) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram). (GRP78 抗体)

FACS

Confocal immunofluorescent analysis of HS Antibody (ABIN388133 and ABIN2846370) with NCI- cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (GRP78 抗体)

Western blot analysis of anti-HS Pab (ABIN388133 and ABIN2846370) in HL60 cell line lysates (35 μg/lane). (GRP78 抗体)

Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with HS antibody (ABIN388133 and ABIN2846370) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (GRP78 抗体)

IHC (p)

Formalin-fixed and paraffin-embedded human Testis tissue reacted with HS antibody (ABIN388133 and ABIN2846370) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (GRP78 抗体)

IHC (p)

6 images

(2 references)

产品编号 ABIN388133

发货至: 中国

Datasheet as PDF

抗原 See all GRP78 (HSPA5) 抗体

GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
适用
190

120

102

36

36

35

33

31

30

20

14

5

5

4

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1
人, 小鼠
宿主
131

94

8

3

1

1
兔
Compatible Secondaries
克隆类型
134

105
多克隆
标记
92

19

16

12

12

12

9

8

8

8

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2
This GRP78 antibody is un-conjugated
应用范围
205

96

82

78

76

33

28

26

26

19

13

7

6

3

3

2

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This HSPA5 antibody is generated from rabbits immunized with a recombinant protein encoding full length human HSPA5.

克隆位点

RB1768

亚型

Ig Fraction

Top Product

Discover our top product HSPA5 Primary Antibody
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) (AA 550-650) antibody
HSPA5 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody
HSPA5 适用: 大鼠 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) (Internal Region) antibody
HSPA5 适用: 人, 大鼠, 小鼠 WB, IF, ICC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) (AA 251-360) antibody
HSPA5 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), FACS, IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) (AA 550-650) antibody
HSPA5 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (HRP)
HSPA5 适用: 大鼠 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal HRP

anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (FITC)
HSPA5 适用: 大鼠 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal FITC

anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (PE)
HSPA5 适用: 大鼠 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal PE

anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (APC)
HSPA5 适用: 大鼠 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal APC

anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (Atto 488)
HSPA5 适用: 大鼠 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal Atto 488

应用备注

IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze-thaw cycles.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

有效期

6 months
Ran, Mao, Shen, Xie, Zhan, Wang, Lu: "GRP78 enabled micelle-based glioma targeted drug delivery." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 255, pp. 120-131, (2018) (PubMed).

Buchkovich, Maguire, Paton, Paton, Alwine: "The endoplasmic reticulum chaperone BiP/GRP78 is important in the structure and function of the human cytomegalovirus assembly compartment." in: Journal of virology, Vol. 83, Issue 22, pp. 11421-8, (2009) (PubMed).
抗原

GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

别名

HSPA5 (HSPA5 产品)

背景

In cooperation with other chaperones, HSP70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. The HSP70s in mitochondria and the endoplasmic reticulum play an additional role by providing a driving force for protein translocation. They are involved in signal transduction pathways in cooperation with HSP90. They participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.

分子量

72333

基因ID

3309

NCBI登录号

NP_005338

UniProt

P11021

途径

Thyroid Hormone Synthesis, ER-Nucleus Signaling