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BNIP3 抗体 (AA 215-252)

BNIP3 适用: 人, 小鼠 IF, IHC (p) 宿主: 兔 Polyclonal RB3385 unconjugated
产品编号 ABIN388117
发货至: 中国
  • 抗原 See all BNIP3 抗体
    BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))
    抗原表位
    • 15
    • 15
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 215-252
    适用
    • 96
    • 43
    • 29
    人, 小鼠
    宿主
    • 83
    • 9
    • 7
    克隆类型
    • 84
    • 15
    多克隆
    标记
    • 37
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This BNIP3 antibody is un-conjugated
    应用范围
    • 53
    • 27
    • 24
    • 18
    • 17
    • 14
    • 13
    • 8
    • 8
    • 4
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This BNIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-252 amino acids from human BNIP3.
    克隆位点
    RB3385
    亚型
    Ig Fraction
    Top Product
    Discover our top product BNIP3 Primary Antibody
  • 应用备注
    IF: 1:500. IF: 1:50~100. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze-thaw cycles.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    有效期
    6 months
  • Karpathiou, Sivridis, Koukourakis, Mikroulis, Bouros, Froudarakis, Bougioukas, Maltezos, Giatromanolaki: "Autophagy and Bcl-2/BNIP3 death regulatory pathway in non-small cell lung carcinomas." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 121, Issue 7, pp. 592-604, (2013) (PubMed).

    Wojtkowiak, Rothberg, Kumar, Schramm, Haller, Proemsey, Lloyd, Sloane, Gillies: "Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments." in: Cancer research, Vol. 72, Issue 16, pp. 3938-47, (2012) (PubMed).

    Metukuri, Beer-Stolz, Namas, Dhupar, Torres, Loughran, Jefferson, Tsung, Billiar, Vodovotz, Zamora: "Expression and subcellular localization of BNIP3 in hypoxic hepatocytes and liver stress." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 296, Issue 3, pp. G499-509, (2009) (PubMed).

  • 抗原
    BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))
    别名
    BNIP3 (NIP3) (BNIP3 产品)
    别名
    NIP3 antibody, Nip3 antibody, BCL2 interacting protein 3 antibody, BCL2/adenovirus E1B interacting protein 3 antibody, BNIP3 antibody, Bnip3 antibody
    背景
    NIP3 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. NIP3 contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein is known to induce apoptosis, even in the presence of BCL2.
    分子量
    27832
    基因ID
    664
    NCBI登录号
    NP_004043
    UniProt
    Q12983
    途径
    Autophagy, Brown Fat Cell Differentiation
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